Interaction of pH-responsive polyanions with phospholipid membranes

被引：8

作者：

Brodszkij, Edit ^{[1
]}

Hviid, Martin J. ^{[1
]}

Ade, Carina ^{[1
]}

Schattling, Philipp S. ^{[1
]}

Burmeister, Moritz ^{[1
]}

Szilagyi, Sven ^{[1
]}

Gal, Noga ^{[1
]}

Zhu, Chuntao ^{[1
,2
]}

Han, Xiaojun ^{[2
]}

Stadler, Brigitte ^{[1
]}

机构：

[1] Aarhus Univ, Interdisciplinary Nanosci Ctr iNANO, Gustav Wieds Vej 14, DK-8000 Aarhus, Denmark

[2] Harbin Inst Technol, State Key Lab Urban Water Resource & Environm, Sch Chem & Chem Engn, 92 West Da Zhi St, Harbin 150001, Heilongjiang, Peoples R China

来源：

POLYMER CHEMISTRY | 2019年 / 10卷 / 44期

关键词：

POLYMERS; DESIGN; PERMEABILITY; DELIVERY; CELL;

D O I：

10.1039/c9py00924h

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

The behavior of two acrylate polymers, with carboxylic acid side groups, was investigated with regard to their pH-responsive interaction with phospholipid membranes. The polyanions crossed the membrane of giant unilamellar vesicles and mammalian cells with low cytotoxicity in the latter case.

引用

页码：5992 / 5997

页数：6

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