Treatment of depression in the elderly with repetitive transcranial magnetic stimulation using theta-burst stimulation: Study protocol for a randomized, double-blind, controlled trial

被引：3
作者：
Valiengo, Leandro [1 ,2 ,3 ]
Pinto, Bianca S. [1 ]
Marinho, Kalian A. P. [1 ]
Santos, Leonardo A. [1 ]
Tort, Luara C. [1 ]
Benatti, Rafael G. [1 ]
Teixeira, Bruna B. [1 ]
Miranda, Cristiane S. [1 ]
Cardeal, Henriette B. [1 ]
Suen, Paulo J. C. [1 ]
Loureiro, Julia C. [1 ]
Vaughan, Renata A. R. [1 ]
Dini Mattar, Roberta A. M. P. F. [1 ]
Lessa, Maira [1 ]
Oliveira, Pedro S. [1 ]
Silva, Valquiria A. [1 ]
Gattaz, Wagner Farid [2 ]
Brunoni, Andre R. [1 ,2 ]
Forlenza, Orestes Vicente [2 ]
机构：
[1] Univ Sao Paulo, Hosp Clin HCFMUSP, Dept & Inst Psychiat, Fac Med,Interdisciplinary Neuromodulat Serv, Sao Paulo, Brazil
[2] Univ Sao Paulo, Hosp Clin HCFMUSP, Fac Med, Dept & Inst Psiquiatria, Sao Paulo, Brazil
[3] Univ Sao Paulo, Fac Med, Programa Fisiopatol Expt, Sao Paulo, Brazil
来源：
FRONTIERS IN HUMAN NEUROSCIENCE | 2022年 / 16卷
关键词：
depression; major depressive disorder; elderly; antidepressant; repetitive transcranial magnetic stimulation (rTMS); theta-burst stimulation (TBS); neuromodulation; MAJOR DEPRESSION; HEART-FAILURE; EFFICACY; RTMS; AGE; MEDICATION; MODULATION; SAFETY; WOMEN; OLDER;
D O I：
10.3389/fnhum.2022.941981
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Introduction: Transcranial magnetic stimulation (TMS) is a consolidated procedure for the treatment of depression, with several meta-analyses demonstrating its efficacy. Theta-burst stimulation (TBS) is a modification of TMS with similar efficacy and shorter session duration. The geriatric population has many comorbidities and a high prevalence of depression, but few clinical trials are conducted specifically for this age group. TBS could be an option in this population, offering the advantages of few side effects and no pharmacological interactions. Therefore, our aim is to investigate the efficacy of TBS in geriatric depression.
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页数：8
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