Novel Fracture Improvements via Vitamin D Supplementation

被引:0
作者
Kazemi, Abolfazl [1 ]
Azar, Masoud Shayesteh [1 ]
Razavipour, Mehran [1 ]
Ghaffari, Salman [1 ]
Khademloo, Mohammad [2 ]
Azade, Hosein [3 ]
机构
[1] Mazandaran Univ Med Sci, Orthoped Res Ctr, Sari, Iran
[2] Mazandaran Univ Med Sci, Dept Community Med, Sch Med, Sari, Iran
[3] Mazandaran Univ Med Sci, Fac Med, Dept Internal Med, Sari, Iran
关键词
Vitamin D; Distal Radius; Fracture; Post-Menopausal; Wrist Function; MUSCLE STRENGTH; D DEFICIENCY; WOMEN; PREVALENCE; FALLS;
D O I
10.5812/traumamon.90745
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Background: Distal radius fracture (DRF) is one of the most common upper limb fractures, which is associated with osteoporosis and vitamin D deficiency, especially in old adults. Objectives: The aim of this study was to evaluate the effect of supplementary vitamin Don grip strength, pinch power, pain intensity, and DASH score in post-menopausal females after distal radius fractures. Methods: Fifty-two post-menopausal women with distal radius fractures were enrolled in a randomized single-blinded multicenter trial from January 2015 to January 2016 (IRCT registration number: IRCT20160830029603N7). Patients with pre-operative serum vitamin D level of 30 to 100 ng/mL were enrolled in the study. Patients were divided into two randomized groups including groups with and without supplementation of vitamin D [25 women in intervention group (50,000 IU supplementary vitamin D, every 4 weeks for 6 months) and 27 women in placebo group]. Grip strength, pinch power, pain intensity, and DASH score pre-operatively and at three and six months after the surgery were measured; the obtained data were analyzed using SPSS version 16. Results: The subjects' mean age in vitamin D supplemented and placebo group was 57.98 +/- 7.15 and 59.15 +/- 8.03, respectively. The mean grip strength of patients in vitamin D supplemented group was significantly higher than the placebo group on both the third and sixth months (P = 0.011 and P= 0.003, respectively). The pinch power was significantly increased on the sixth month compared to the third month in patients with revised vitamin D supplementation (1.32 +/- 2.14 and 0.67 +/- 0.96 respectively, P = 0.0001). There was no statistically significant difference between the two groups in terms of mean VAS and DASH scores at the end of the study (P = 241, P = 0.665, respectively). Conclusions: Vitamin D supplementation was significantly helpful in improving grip strength recovery in post-menopausal women after distal radius fracture, however, no significant differences were observed in supplementation of vitamin D on pinch power and pain intensity after distal radius fractures.
引用
收藏
页数:5
相关论文
共 50 条
[41]   The necessity of gestational vitamin D supplementation depends on ambient temperature: concern for infant vitamin D status [J].
Yin, Wanjun ;
Zhang, Lei ;
Zhu, Peng .
FRONTIERS IN NUTRITION, 2025, 12
[42]   What Is the Role of Vitamin D Supplementation in Acute Fracture Patients? A Systematic Review and Meta-Analysis of the Prevalence of Hypovitaminosis D and Supplementation Efficacy [J].
Sprague, Sheila ;
Petrisor, Brad ;
Scott, Taryn ;
Devji, Tahira ;
Phillips, Mark ;
Spurr, Hayley ;
Bhandari, Mohit ;
Slobogean, Gerard P. .
JOURNAL OF ORTHOPAEDIC TRAUMA, 2016, 30 (02) :53-63
[43]   Is Supplementation of Vitamin D Beneficial for Fracture Healing? A Short Review of the Literature [J].
Eschle, Daniel ;
Aeschlimann, Andre G. .
GERIATRIC ORTHOPAEDIC SURGERY & REHABILITATION, 2011, 2 (03) :90-93
[44]   Vitamin D Level Stability in Dystrophinopathy Patients on Vitamin D Supplementation [J].
Vather-Wu, Naomi ;
Krasowski, Matthew D. ;
Mathews, Katherine D. ;
Shibli-Rahhal, Amal .
JOURNAL OF NEUROMUSCULAR DISEASES, 2021, 8 (04) :481-487
[45]   Vitamin D and Fracture Prevention [J].
Bischoff-Ferrari, Heike A. .
ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 2010, 39 (02) :347-+
[46]   Vitamin D and Fracture Prevention [J].
Bischoff-Ferrari, Heike A. .
RHEUMATIC DISEASE CLINICS OF NORTH AMERICA, 2012, 38 (01) :107-+
[47]   Effects of vitamin D supplementation on the functional outcome in patients with osteoporotic vertebral compression fracture and vitamin D deficiency [J].
Sangbong Ko ;
ChungMu Jun ;
Junho Nam .
Journal of Orthopaedic Surgery and Research, 16
[48]   Effects of vitamin D supplementation on the functional outcome in patients with osteoporotic vertebral compression fracture and vitamin D deficiency [J].
Ko, Sangbong ;
Jun, ChungMu ;
Nam, Junho .
JOURNAL OF ORTHOPAEDIC SURGERY AND RESEARCH, 2021, 16 (01)
[49]   Vitamin D supplementation in adults - guidelines [J].
Marcinowska-Suchowierska, Ewa ;
Walicka, Magdalena ;
Talalaj, Marek ;
Horst-Sikorska, Wanda ;
Ignaszak-Szczepaniak, Magdalena ;
Sewerynek, Ewa .
ENDOKRYNOLOGIA POLSKA, 2010, 61 (06) :723-729
[50]   Vitamin D supplementation in the ICU patient [J].
Christopher, Kenneth B. .
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE, 2015, 18 (02) :187-192