Mechanical properties and corrosion resistance of powder metallurgical Mg-Zn-Ca/Fe bulk metal glass composites for biomedical application

被引：35

作者：

Li, Kun ^{[1
]}

Liang, Luxin ^{[2
]}

Du, Peng ^{[1
]}

Cai, Zeyun ^{[1
]}

Xiang, Tao ^{[1
]}

Kanetaka, Hiroyasu ^{[3
,4
]}

Wu, Hong ^{[2
]}

Xie, Guoqiang ^{[1
,5
]}

机构：

[1] Harbin Inst Technol Shenzhen, Sch Mat Sci & Engn, Shenzhen 518055, Peoples R China

[2] Cent South Univ, State Key Lab Powder Met, Changsha 410083, Peoples R China

[3] Tohoku Univ, Grad Sch Biomed Engn, Sendai, Miyagi 9808579, Japan

[4] Tohoku Univ, Grad Sch Dent, Sendai, Miyagi 9808575, Japan

[5] Harbin Inst Technol, State Key Lab Adv Welding & Joining, Harbin 150001, Peoples R China

来源：

JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY | 2022年 / 103卷

基金：

中国国家自然科学基金;

关键词：

Mg-66; Zn-30; Ca-4; Fe bulk metallic glass; composites; Spark plasma sintering; Corrosion behaviour; Mechanical strength; IN-VITRO; DEGRADATION BEHAVIOR; AMORPHOUS-ALLOYS; PERFORMANCE; SR; CYTOTOXICITY; ZINC; VIVO;

D O I：

10.1016/j.jmst.2021.07.006

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Magnesium (Mg) alloys can be regarded as the most promising biodegradable implant materials for orthopedic and stent applications due to their good biocompatibility and low Young???s modulus which is near to that of natural bone. However, its applicability is hindered because it exhibits a high corrosion rate in the physiological environments. In this work, we fabricated Mg 66 Zn 30 Ca 4 /Fe bulk metallic glass composites via spark plasma sintering (SPS). We studied the influence of different contents of Fe on the properties of the composites. The results indicated that Fe was uniformly distributed on the surface of Mg 66 Zn 30 Ca 4 metallic glass (MG) as a second phase, which led to an improvement in the corrosion resistance and mechanical strength. The standard potential of Mg 66 Zn 30 Ca 4 /Fe bulk metallic glass (BMG) composites increased as compared to Mg 66 Zn 30 Ca 4 , while their mechanical strength improved from 355 MPa to 616 MPa. Furthermore, cytotoxicity was investigated via the CCK-8 assay and calcein-AM staining, which revealed that the extraction mediums diluted 6 times (EM ?? 6) of the Mg 66 Zn 30 Ca 4 and Mg 66 Zn 30 Ca 4 /Fe did not cause cell toxicity on day 3 and 5, while the EM ?? 6 of the Mg 66 Zn 30 Ca 4 showed cytotoxicity on day 1, 3 and 5. Thus, Mg 66 Zn 30 Ca 4 /Fe BMG composites exhibit significant potential for fabricating implants with good mechanical strength and corrosion resistance. ?? 2022 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology.

引用

页码：73 / 83

页数：11

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