A new N-methoxyl-carbonyl benzylisoquinoline from Litsea cubeba

被引：4
|
作者：
Tang, Bin [1 ]
Tu, Hua [1 ]
Long, Han-An [1 ]
Du, Jun [1 ]
Guo, Jian-Min [1 ]
Liu, Hong-Jin [2 ]
Hu, Xin [3 ]
Yang, Li [4 ]
Du, Xi [1 ]
机构：
[1] Southwest Med Univ, Basic Med Coll, Luzhou 646100, Peoples R China
[2] Southwest Med Univ, Affiliated Hosp 1, Luzhou 646000, Peoples R China
[3] Southwest Med Univ, Affiliated Hosp 2, Luzhou 646000, Peoples R China
[4] Yibin Univ, Coll Chem & Chem Engn, Yibin 644007, Peoples R China
来源：
JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH | 2017年 / 19卷 / 09期
关键词：
Lauraceae; Litsea cubeba; benzylisoquinoline; X-ray diffraction; cytotoxicity; ISOQUINOLINE ALKALOIDS;
D O I：
10.1080/10286020.2016.1275582
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
A new benzylisoquinoline alkaloid (center dot)-N-methoxycarbonyl-norjuziphine (1) was isolated from Litsea cubeba. Its structure was identified by extensively spectroscopic techniques and confirmed by the single-crystal X-ray diffraction analysis. Compound 1 showed cytotoxicity against HL-60 and MCF-7 cells, with IC50 values of 18.1 and 15.0M, respectively, comparable to 3.1 and 17.5M of the cisplatin (positive control).
引用
收藏
页码：941 / 945
页数：5
相关论文
共 50 条
  • [31] N-alkylamides from Litsea cubeba (Lour.) Pers. with potential anti-inflammatory activity
    Shen, Guo-Dong
    Zhang, Yin-Yan
    Yang, Nian-Qi
    Yang, Tong
    Wang, Ting
    Lu, Shi-Cheng
    Wang, Jin-Yun
    Wang, Yun-Song
    Yang, Jing-Hua
    NATURAL PRODUCT RESEARCH, 2024, 38 (10) : 1727 - 1738
  • [32] Simulation of the Vacuum Distillation Separating Process of Citral from Litsea cubeba Oil
    Xianshu WANG
    Qin WANG
    Jiannan SHI
    Medicinal Plant, 2013, (01) : 8 - 10
  • [33] Synthesis of SnO2 nanoparticles using extracts from Litsea cubeba fruits
    Hong, Gui-Bing
    Jiang, Chun-Jie
    MATERIALS LETTERS, 2017, 194 : 164 - 167
  • [34] Potential cosmetic application of essential oil extracted from Litsea cubeba fruits from China
    Huang, Xiao-Wei
    Feng, Yun-Chao
    Huang, Yi
    Li, Hai-Ling
    JOURNAL OF ESSENTIAL OIL RESEARCH, 2013, 25 (02) : 112 - 119
  • [35] Molecular cloning and characterization of monoterpene synthases from Litsea cubeba (Lour.) Persoon
    Chang, Yueh-Te
    Chu, Fang-Hua
    TREE GENETICS & GENOMES, 2011, 7 (04) : 835 - 844
  • [36] Essential Oil Compositions and Antimicrobial Activities of Various Parts of Litsea cubeba from Taiwan
    Su, Yu-Chang
    Ho, Chen-Lung
    NATURAL PRODUCT COMMUNICATIONS, 2016, 11 (04) : 515 - 518
  • [37] Molecular cloning and characterization of monoterpene synthases from Litsea cubeba (Lour.) Persoon
    Yueh-Te Chang
    Fang-Hua Chu
    Tree Genetics & Genomes, 2011, 7 : 835 - 844
  • [38] Compositions and in vitro Anticancer activities of the Leaf and Fruit Oils of Litsea cubeba from Taiwan
    Ho, Chen-Lung
    Jie-Ping, Ou
    Liu, Yao-Chi
    Hung, Chien-Ping
    Tsai, Ming-Chih
    Liao, Pei-Chun
    Wang, Eugene I-Chen
    Chen, Yi-Lin
    Su, Yu-Chang
    NATURAL PRODUCT COMMUNICATIONS, 2010, 5 (04) : 617 - 620
  • [39] Chemical Composition and Antibacterial Activity of Essential Oils from Different Parts of Litsea cubeba
    Wang, Hongwu
    Liu, Yanqing
    CHEMISTRY & BIODIVERSITY, 2010, 7 (01) : 229 - 235
  • [40] Anti-inflammatory activity of neral and geranial isolated from fruits of Litsea cubeba Lour
    Liao, Pei-Chun
    Yang, Tsung-Shi
    Chou, Ju-Ching
    Chen, Jie
    Lee, Shu-Ching
    Kuo, Yueh-Hsiung
    Ho, Chen-Lung
    Chao, Louis Kuo-Ping
    JOURNAL OF FUNCTIONAL FOODS, 2015, 19 : 248 - 258
12345