Adult Acute Lymphoblastic Leukemia: Treatment and Management Updates

被引：20

作者：

Gregory, Stephanie ^{[1
]}

机构：

[1] CMR 415,Box 7835, APO, AE 09114 USA

来源：

SEMINARS IN ONCOLOGY NURSING | 2019年 / 35卷 / 06期

关键词：

novel therapies; acute lymphoblastic leukemia; blinatumumab; CAR-T cell therapy; bispecific antibodies; inotuzumab ozogamicin; cytokine release syndrome; CYTOKINE RELEASE SYNDROME; RECEPTOR T-CELLS; BLINATUMOMAB; THERAPY; ANTIBODIES; TOXICITIES;

D O I：

10.1016/j.soncn.2019.150951

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Objective: To present an overview of novel therapies for the treatment of adult acute lymphoblastic leukemia and to discuss nursing implications for these new therapies. Data Sources: Published manuscripts, Web sites, and pharmaceutical package inserts. Conclusion: Several promising therapies have emerged in the treatment of relapsed/refractory and minimal residual disease acute lymphoblastic leukemia. Implications for Nursing Practice: With the changing paradigm for hematologic malignancies, nurses must remain current in their knowledge regarding novel therapies, including their administration, toxicity profile, and management of adverse events. This article addresses the clinical benefits of novel agents and nursing implications for those agents. (C) 2019 Elsevier Inc. All rights reserved.

引用

页数：4

共 30 条

[1] Associated Toxicities Assessment and management related to CAR T-cell therapy [J].

Anderson, Karen ;

Latchford, Theresa .

CLINICAL JOURNAL OF ONCOLOGY NURSING, 2019, 23 (02) :13-19

[2]

[Anonymous], 2018, Besponsa [package insert]

[3]

[Anonymous], 2018, BLOOD S1, DOI DOI 10.1182/BLOOD-2018-99-111531

[4]

[Anonymous], 2017, KYMRIAH PACKAGE INSE

[5] Safety and Efficacy of Blinatumomab in Combination With a Tyrosine Kinase Inhibitor for the Treatment of Relapsed Philadelphia Chromosome-positive Leukemia [J].

Assi, Rita ;

Kantarjian, Hagop ;

Short, Nicholas J. ;

Daver, Naval ;

Takahashi, Koichi ;

Garcia-Manero, Guillermo ;

DiNardo, Courtney ;

Burger, Jan ;

Cortes, Jorge ;

Jain, Nitin ;

Wierda, William ;

Chamoun, Salim ;

Konopleva, Marina ;

Jabbour, Elias .

CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2017, 17 (12) :897-901

[6] Association of Minimal Residual Disease With Clinical Outcome in Pediatric and Adult Acute Lymphoblastic Leukemia AMeta-analysis [J].

Berry, Donald A. ;

Zhou, Shouhao ;

Higley, Howard ;

Mukundan, Lata ;

Fu, Shuangshuang ;

Reaman, Gregory H. ;

Wood, Brent L. ;

Kelloff, Gary J. ;

Jessup, J. Milburn ;

Radich, Jerald P. .

JAMA ONCOLOGY, 2017, 3 (07)

[7] Toxicities of chimeric antigen receptor T cells: recognition and management [J].

Brudno, Jennifer N. ;

Kochenderfer, James N. .

BLOOD, 2016, 127 (26) :3321-3330

[8]

Callahan C, 2017, CLIN J ONCOL NURS, V17, P897

[9] Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia [J].

Davila, Marco L. ;

Riviere, Isabelle ;

Wang, Xiuyan ;

Bartido, Shirley ;

Park, Jae ;

Curran, Kevin ;

Chung, Stephen S. ;

Stefanski, Jolanta ;

Borquez-Ojeda, Oriana ;

Olszewska, Malgorzata ;

Qu, Jinrong ;

Wasielewska, Teresa ;

He, Qing ;

Fink, Mitsu ;

Shinglot, Himaly ;

Youssif, Maher ;

Satter, Mark ;

Wang, Yongzeng ;

Hosey, James ;

Quintanilla, Hilda ;

Halton, Elizabeth ;

Bernal, Yvette ;

Bouhassira, Diana C. G. ;

Arcila, Maria E. ;

Gonen, Mithat ;

Roboz, Gail J. ;

Maslak, Peter ;

Douer, Dan ;

Frattini, Mark G. ;

Giralt, Sergio ;

Sadelain, Michel ;

Brentjens, Renier .

SCIENCE TRANSLATIONAL MEDICINE, 2014, 6 (224)

[10] Cytokine release syndrome: Who is at risk and how to treat [J].

Frey, Noelle .

BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY, 2017, 30 (04) :336-340

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