Sarcoma of the Uterus. Guideline of the DGGG, OEGGG and SGGG (S2k-Level, AWMF Registry No.015/074, April 2021)

被引:15
作者
Denschlag, Dominik [1 ]
Ackermann, Sven [2 ]
Battista, Marco Johannes [3 ]
Cremer, Wolfgang [4 ]
Egerer, Gerlinde [5 ]
Fehr, Matthias [6 ]
Follmann, Markus [7 ]
Haase, Heidemarie [8 ]
Harter, Philipp [9 ]
Hettmer, Simone [10 ]
Horn, Lars-Christian [11 ]
Juhasz-Boess, Ingolf [12 ]
Kast, Karin [13 ]
Koehler, Guenter [14 ]
Kroencke, Thomas [15 ]
Lindel, Katja [16 ]
Mallmann, Peter [17 ]
Meyer-Steinacker, Regine [18 ]
Mustea, Alexander [19 ]
Petru, Edgar [20 ]
Reichardt, Peter [21 ]
Schmidt, Dietmar [22 ]
Strauss, Hans-Georg [23 ]
Thiel, Falk
Ulrich, Uwe Andreas [24 ]
Vogl, Thomas [25 ]
Vordermark, Dirk [26 ]
Wallwiener, Markus [27 ]
Gass, Paul [28 ]
Beckmann, MatthiasW. [28 ]
机构
[1] Hochtaunuskliniken Bad Homburg, Frauenklin, Bad Homburg, Germany
[2] Klinikum Darmstadt, Frauenklin, Darmstadt, Germany
[3] Univ Med Mainz, Klin & Poliklin Geburtshilfe & Frauengesundheit, Mainz, Germany
[4] Berufsverband Frauenarzte, Hamburg, Germany
[5] Univ Klin Heidelberg, Heidelberg, Germany
[6] Kantonsspital Frauenfeld, Frauenfeld, Switzerland
[7] Deutsch Krebsgesellschaft, Berlin, Germany
[8] Frauenselbsthilfe nach Krebs eV, Erlangen, Germany
[9] Kliniken Essen Mitte, Klin Gynakol & Gynakolog Onkol, Essen, Germany
[10] Univ Klin Freiburg, Freiburg, Germany
[11] Univ Klinikum Leipzig, Inst Pathol, Abt Mamma Urogenital & Perinatalpathol, Leipzig, Germany
[12] Univ Klinikum Freiburg, Frauenklin, Freiburg, Germany
[13] Univ Klinikum Koln, Natl Zentrum Familiare Tumorerkrankungen NCFT, Cologne, Germany
[14] Univ Med Greifswald, Deutsch Klin Kompetenzzentrum Genitale Sarkome &, Greifswald, Germany
[15] Klinikum Augsburg, Radiol Klin, Augsburg, Germany
[16] Klinikum Karlsruhe, Klin Radioonkol, Karlsruhe, Germany
[17] Univ Klinikum Koln, Klin & Poliklin Frauenheilkunde & Geburtshilfe, Cologne, Germany
[18] Univ Klin Ulm, Ulm, Germany
[19] Univ Klinikum Bonn, Klin Gynakol & Gynakolog Onkol, Bonn, Germany
[20] Med Univ Graz, Univ Klin Frauenheilkunde & Geburtshilfe, Graz, Austria
[21] Helios Kliniken Berlin Buch, Klin Interdisziplinare Onkol, Berlin, Germany
[22] MVZ Histol Zytol & Mol Diagnost, Trier, Germany
[23] Univ Klinikum Halle, Klin & Poliklin Gynakol, Halle, Saale, Germany
[24] Martin Luther Krankenhaus Berlin, Klin Gynakol & Geburtshilfe, Johannesstift Diakonie, Berlin, Germany
[25] Univ Klinikum Frankfurt, Inst Diagnost & Intervent Radiol, Frankfurt, Germany
[26] Univ Klinikum Halle, Univ & Poliklin Strahlentherapie, Halle, Saale, Germany
[27] Univ Klinikum Heidelberg, Frauenklin, Heidelberg, Germany
[28] Friedrich Alexander Univ Erlangen Nurnberg FAU, Frauenklin Univ Erlangen, Comprehens Canc Ctr Erlangen Europa Metropol Reg, Erlangen, Germany
关键词
guideline; uterine sarcoma; leiomyosarcoma; endometrial stromal sarcoma; adenosarcoma; morcellation; ENDOMETRIAL STROMAL SARCOMA; PHASE-II TRIAL; UNCONTAINED POWER MORCELLATION; UNEXPECTED UTERINE SARCOMA; SMOOTH-MUSCLE TUMORS; PROGNOSTIC-FACTORS; PULMONARY METASTASES; HIGH-GRADE; SUPRACERVICAL HYSTERECTOMY; LAPAROSCOPIC MYOMECTOMY;
D O I
10.1055/a-1897-5124
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Purpose This is an official guideline, published and coordinated by the Germany Society for Gynecology and Obstetrics (Deutsche Gesellschaft fur Gynakologie und Geburtshilfe, DGGG). Because of their rarity and heterogeneous histopathology, uterine sarcomas are challenging in terms of their clinical management and therefore require a multidisciplinary approach. To our knowledge, there are currently no binding evidence-based recommendations for the appropriate management of this heterogeneous group of tumors. Methods This S2k guideline was first published in 2015. The update published here is once again the result of the consensus of a representative interdisciplinary committee of experts who were commissioned by the Guidelines Committee of the DGGG to carry out a systematic search of the literature on uterine sarcomas. Members of the participating professional societies achieved a formal consensus after a structured consensus process. Recommendations 1.1 Epidemiology, classification, staging of uterine sarcomas. 1.2 Symptoms, general diagnostic workup, general pathology or genetic predisposition to uterine sarcomas. 2. Management of leiomyosarcomas. 3. Management of low- grade endometrial stromal sarcomas. 4. Management of high-grade endometrial stromal sarcoma and undifferentiated uterine sarcomas. 5. Management of adenosarcomas. 6. Rhabdomyosarcomas of the uterus in children and adolescents. 7. Follow-up of uterine sarcomas. 8. Management of morcellated uterine sarcomas. 9. Information provided to patients.
引用
收藏
页码:1337 / 1367
页数:31
相关论文
共 136 条
[1]   Clinical study investigating the role of lymphadenectomy, surgical castration and adjuvant hormonal treatment in endometrial stromal sarcoma [J].
Amant, F. ;
De Knijf, A. ;
Van Calster, B. ;
Leunen, K. ;
Neven, P. ;
Berteloot, P. ;
Vergote, I. ;
Van Huffel, S. ;
Moerman, P. .
BRITISH JOURNAL OF CANCER, 2007, 97 (09) :1194-1199
[2]   Clinical management of uterine sarcomas [J].
Amant, Frederic ;
Coosemans, An ;
Debiec-Rychter, Maria ;
Timmerman, Dirk ;
Vergote, Ignace .
LANCET ONCOLOGY, 2009, 10 (12) :1188-1198
[3]  
[Anonymous], 2014, COOPERATIVE WEICHTEI
[4]  
[Anonymous], 2014, STATEMENT SOC GYNECO
[5]  
[Anonymous], 2014, MORCELLATION UTERINE
[6]   Pulmonary metastases from uterine malignancies: Results of surgical resection in 133 patients [J].
Anraku, M ;
Yokoi, K ;
Nakagawa, K ;
Fujisawa, T ;
Nakajima, J ;
Akiyama, H ;
Nishimura, Y ;
Kobayashi, K .
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY, 2004, 127 (04) :1107-1112
[7]   Ovary and uterus-sparing procedures for low-grade endometrial stromal sarcoma: A retrospective study of 153 cases [J].
Bai, Huimin ;
Yang, Jiaxin ;
Cao, Dongyan ;
Huang, Huifang ;
Xiang, Yang ;
Wu, Ming ;
Cui, Quancai ;
Chen, Jie ;
Lang, Jinghe ;
Shen, Keng .
GYNECOLOGIC ONCOLOGY, 2014, 132 (03) :654-660
[8]  
Baniak N., INT J SURG PATHOL
[9]   Does Radiotherapy or Lymphadenectomy improve Survival in Endometrial Stromal Sarcoma? [J].
Barney, Brandon ;
Tward, Jonathan D. ;
Skidmore, Thomas ;
Gaffney, David K. .
INTERNATIONAL JOURNAL OF GYNECOLOGICAL CANCER, 2009, 19 (07) :1232-1238
[10]   Surgical Methods for the Treatment of Uterine Fibroids - Risk of Uterine Sarcoma and Problems of Morcellation: Position Paper of the DGGG [J].
Beckmann, M. ;
Juhasz-Boess, I. ;
Denschlag, D. ;
Gass, P. ;
Dimpfl, T. ;
Harter, P. ;
Mallmann, P. ;
Renner, S. P. ;
Rimbach, S. ;
Runnebaum, I. ;
Untch, M. ;
Brucker, S. Y. ;
Wallwiener, D. .
GEBURTSHILFE UND FRAUENHEILKUNDE, 2015, 75 (02) :148-164