Primary cutaneous aggressive epidermotropic CD8+ T-cell lymphoma

被引：42

作者：

Gormley, Rachel H. ^{[1
]}

Hess, Stephen D. ^{[1
]}

Anand, Dipti ^{[2
]}

Junkins-Hopkins, Jacqueline ^{[3
]}

Rook, Alain H. ^{[1
]}

Kim, Ellen J. ^{[1
]}

机构：

[1] Univ Penn, Sch Med, Dept Dermatol, Philadelphia, PA 19104 USA

[2] Univ Penn, Sch Med, Dept Pathol & Lab Med, Philadelphia, PA 19104 USA

[3] Johns Hopkins Sch Med, Dept Dermatol, Baltimore, MD USA

来源：

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY | 2010年 / 62卷 / 02期

关键词：

cutaneous T-cell lymphoma; primary cutaneous epidermotropic CD8(+) cutaneous T-cell lymphoma; EUROPEAN-ORGANIZATION; EORTC CLASSIFICATION; CLINICAL BEHAVIOR; MYCOSIS-FUNGOIDES; SEZARY-SYNDROME; TASK-FORCE; CD8+; SKIN; PATIENT; INVOLVEMENT;

D O I：

10.1016/j.jaad.2009.02.035

中图分类号：

R75 [皮肤病学与性病学];

学科分类号：

100206 ;

摘要：

Cutaneous T-cell lymphomas most commonly have a CD4(+) memory T-cell phenotype with relatively indolent course, but May in rare Cases present with a CD8(+) cytotoxic phenotype exhibiting strikingly more aggressive clinical behavior. We present two cases of the clinically aggressive subtype of primary cutaneous epidermotropic CD8(+) cutaneous T-cell lymphomas and review the current literature, clinical behavior, and recommendations for treatment distinct from that of more common CD4(+) variants of cutaneous T-cell lymphoma. (J Am Acad Dermatol 2010;62:300-7.)

引用

页码：300 / 307

页数：8

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