Electrochemical detection modes for microchip capillary electrophoresis

被引：51
|
作者：
Xu, Jing-Juan [1 ]
Wang, Ai-Jun [1 ]
Chen, Hong-Yuan [1 ]
机构：
[1] Nanjing Univ, Sch Chem & Chem Engn, Key Lab Analyt Chem Life Sci, Nanjing 210093, Peoples R China
来源：
TRAC-TRENDS IN ANALYTICAL CHEMISTRY | 2007年 / 26卷 / 02期
基金：
中国国家自然科学基金;
关键词：
amperometric detection; ECD; electrochemical detection; microchip capillary electrophoresis; mu-CE; separation electric field;
D O I：
10.1016/j.trac.2006.08.006
中图分类号：
O65 [分析化学];
学科分类号：
070302 ; 081704 ;
摘要：
The interest in microchip capillary electrophoresis (mu-CE) with electrochemical detection (ECD) has increased considerably because ECD offers perfect features for mu-CE, including remarkable sensitivity, inherent miniaturization and portability, low cost, low-power requirements and great compatibility with microfabrication technologies. This review focuses on recent advances in integrating ECD, especially amperometric detection, with mu-CE. We discuss in detail effects of the separation electric field and development of strategies for isolating and not isolating detection from the separation electric field. We expect that mu-CE-ECD will become a powerful tool for clinical diagnostics, environmental monitoring and biological assays. (c) 2006 Elsevier Ltd. All rights reserved.
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页码：125 / 132
页数：8
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