Anti-platelet stilbenes from aerial parts of Rheum palaestinum

被引:63
作者
Aburjai, TA [1 ]
机构
[1] Univ Jordan, Fac Pharm, Dept Pharmaceut Sci, Amman, Jordan
关键词
Rheum palaestinum; Polygonaceae; Piceid; rhaponticin; Chrysophanoi; anti-platelet;
D O I
10.1016/S0031-9422(00)00341-1
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A chemical investigation of biologically active compounds from the aerial parts of Rheum palaestinum has led to the isolation and identification of two stilbenes; trans-resveratrol-3-O-beta -D-glucopyranosid (I) and rhaponticin (II). The structures of these stilbenes were established on the basis of spectroscopic data including MS and NMR. Compounds (I) and (II) have been shown to exhibit anti-platelet activity. Moreover, chrysophanol was also identified and characterized. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:407 / 410
页数:4
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