Two novel diterpenoids, erinacines H and I from the mycelia of Hericium erinaceum

被引：146
作者：
Lee, EW
Shizuki, K
Hosokawa, S
Suzuki, M
Suganuma, H
Inakuma, T
Li, JX
Ohnishi-Kameyama, M
Nagata, T
Furukawa, S
Kawagishi, H
机构：
[1] Shizuoka Univ, Fac Agr, Dept Appl Biol Chem, SHIZUOKA 4228529, Japan
[2] Kagome Co Ltd, Res Inst, Nishinasuno, Tochigi 3292762, Japan
[3] Jilin Inst Biol, Changchun, Peoples R China
[4] Minist Agr Forestry & Fisheries, Natl Food Res Inst, Tsukuba, Ibaraki 3058642, Japan
[5] NIAI, Dept Anim Prod, Kukizaki, Ibaraki 3050901, Japan
[6] Gifu Pharmaceut Univ, Dept Mol Biol, Gifu 5025858, Japan
来源：
BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY | 2000年 / 64卷 / 11期
关键词：
Hericium erinaceum; nerve growth factor; stimulator; diterpenoid;
D O I：
10.1271/bbb.64.2402
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Novel diterpenoids, erinacines H (1) and 1(3), were isolated from the cultured mycelia of Hericium erinaceum. The structures of the compounds were determined by interpretation of the spectral data. Erinacine EI showed stimulating activity of nerve growth factor (NGF)-synthesis.
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收藏
页码：2402 / 2405
页数：4
相关论文
共 17 条
[1]   METABOLITES OF CYATHUS-HELENAE - NEW CLASS OF DITERPENOIDS [J].
AYER, WA ;
TAUBE, H .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1973, 51 (23) :3842-&
[2]   METABOLITES OF BIRDS NEST FUNGI .10. C-13 NUCLEAR MAGNETIC-RESONANCE STUDIES ON CYATHINS [J].
AYER, WA ;
NAKASHIMA, TT ;
WARD, DE .
CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1978, 56 (16) :2197-2199
[3]   SYNTHESIS AND SECRETION OF NERVE GROWTH-FACTOR BY MOUSE ASTROGLIAL CELLS IN CULTURE [J].
FURUKAWA, S ;
FURUKAWA, Y ;
SATOYOSHI, E ;
HAYASHI, K .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1986, 136 (01) :57-63
[4]   REGULATION OF NERVE GROWTH-FACTOR SYNTHESIS SECRETION BY CATECHOLAMINE IN CULTURED MOUSE ASTROGLIAL CELLS [J].
FURUKAWA, S ;
FURUKAWA, Y ;
SATOYOSHI, E ;
HAYASHI, K .
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1987, 147 (03) :1048-1054
[5]  
FURUKAWA Y, 1986, J BIOL CHEM, V261, P6039
[6]   ALIPHATIC SIDE-CHAIN OF CATECHOLAMINE POTENTIATES THE STIMULATORY EFFECT OF THE CATECHOL PART ON THE SYNTHESIS OF NERVE GROWTH-FACTOR [J].
FURUKAWA, Y ;
FURUKAWA, S ;
IKEDA, F ;
SATOYOSHI, E ;
HAYASHI, K .
FEBS LETTERS, 1986, 208 (02) :258-262
[7]   HERICENONE-C, HERICENONE-D AND HERICENONE-E, STIMULATORS OF NERVE GROWTH-FACTOR (NGF)-SYNTHESIS, FROM THE MUSHROOM HERICIUM-ERINACEUM [J].
KAWAGISHI, H ;
ANDO, M ;
SAKAMOTO, H ;
YOSHIDA, S ;
OJIMA, F ;
ISHIGURO, Y ;
UKAI, N ;
FURUKAWA, S .
TETRAHEDRON LETTERS, 1991, 32 (35) :4561-4564
[8]   Dictyophorines A and B, two stimulators of NGF-synthesis from the mushroom Dictyophora indusiata [J].
Kawagishi, H ;
Ishiyama, D ;
Mori, H ;
Sakamoto, H ;
Ishiguro, Y ;
Furukawa, S ;
Li, JX .
PHYTOCHEMISTRY, 1997, 45 (06) :1203-1205
[9]  
Kawagishi H, 1996, HETEROCYCL COMMUN, V2, P51
[10]   Erinacines E, F, and G, stimulators of nerve growth factor (NGF)-synthesis, from the mycelia of Hericium erinaceum [J].
Kawagishi, H ;
Shimada, A ;
Hosokawa, S ;
Mori, H ;
Sakamoto, H ;
Ishiguro, Y ;
Sakemi, S ;
Bordner, J ;
Kojima, N ;
Furukawa, S .
TETRAHEDRON LETTERS, 1996, 37 (41) :7399-7402
12