Adverse effects of antiretroviral therapy

被引：783
|
作者：
Carr, A [1 ]
Cooper, DA
机构：
[1] St Vincents Hosp, HIV Immunol & Infect Dis Clin Serv Unit, Sydney, NSW 2010, Australia
[2] Univ New S Wales, Natl Ctr HIV Epidemiol & Clin Res, Sydney, NSW, Australia
来源：
LANCET | 2000年 / 356卷 / 9239期
关键词：
D O I：
10.1016/S0140-6736(00)02854-3
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Antiretroviral toxicity is an increasingly important issue in the management of HIV infected patients. With the sustained major declines in opportunistic complications, HIV infection is a more chronic disease, and so more drugs are being used in more patients for longer periods. This review focuses on the pathogenesis, clinical features, and management of the principal toxicities of the 15 licensed antiretroviral drugs, including mitochondrial toxicity, hypersensitivity, and lipodystrophy, as well as more drug-specific adverse effects and special clinical settings.
引用
收藏
页码：1423 / 1430
页数：8
相关论文
共 50 条
  • [41] Antiretroviral therapy during pregnancy and the risk of an adverse outcome
    Tuomala, RE
    Shapiro, DE
    Mofenson, LM
    Bryson, Y
    Culnane, M
    Hughes, MD
    O'Sullivan, MJ
    Scott, G
    Stek, AM
    Wara, D
    Bulterys, M
    NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (24) : 1863 - 1870
  • [42] The adverse events of antiretroviral therapy (ARVRx) as a cause of hospitalisation
    Latarska, D
    Podlasin, R
    Dska, JG
    Grabczewski, P
    Koch, K
    Pastuszka, E
    Wierzchowska, I
    Sawicka, B
    AIDS, 2000, 14 : S68 - S68
  • [43] Common Adverse Effects of Antiretroviral Therapy for HIV Disease (vol 83, pg 1443, 2011)
    Reust, Carine E.
    AMERICAN FAMILY PHYSICIAN, 2011, 84 (02) : 154 - 154
  • [44] Adverse effects of standard first-line antiretroviral therapy on black South African patients
    Georg, J. A.
    Lutchman, N.
    Crowther, N. J.
    ANTIVIRAL THERAPY, 2007, 12 (06) : L44 - L44
  • [45] Management of common adverse effects in the era of highly active antiretroviral therapy in south east Ethiopia
    Abdella, Sadikalmahdi Hussen
    Wabe, Nasir Tajure
    Yesuf, Elias Ali
    NORTH AMERICAN JOURNAL OF MEDICAL SCIENCES, 2011, 3 (11) : 499 - 502
  • [46] The side effects of antiretroviral therapy
    Hartmann, M.
    HAUTARZT, 2006, 57 (11): : 969 - 974
  • [47] Immunological effects of antiretroviral therapy
    Cooper, DA
    ANTIVIRAL THERAPY, 1998, 3 : 19 - 23
  • [48] Adverse effects of chronic treatment with the Main subclasses of highly active antiretroviral therapy: a systematic review
    Silva, B. F.
    Peixoto, G. M. L.
    da Luz, S. R.
    de Moraes, S. M. F.
    Peres, S. B.
    HIV MEDICINE, 2019, 20 (07) : 429 - 438
  • [49] Antitumour effects of antiretroviral therapy
    Paolo Monini
    Cecilia Sgadari
    Elena Toschi
    Giovanni Barillari
    Barbara Ensoli
    Nature Reviews Cancer, 2004, 4 : 861 - 875
  • [50] Antitumour effects of antiretroviral therapy
    Monini, P
    Sgadari, C
    Toschi, E
    Barillari, G
    Ensoli, B
    NATURE REVIEWS CANCER, 2004, 4 (11) : 861 - 875
12345