γδ T cells:: Non-classical ligands for non-classical cells

被引:29
作者
Steele, CR [1 ]
Oppenheim, DE [1 ]
Hayday, AC [1 ]
机构
[1] Guys Hosp, GKT Sch Med, Dept Immunobiol, London SE1 9RT, England
基金
英国惠康基金;
关键词
D O I
10.1016/S0960-9822(00)00408-5
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
A recent study describes direct binding between a gamma delta T-cell receptor and its ligand, T22, a non-classical class I major histocompatibility complex (MHC) molecule. A companion study, solving the crystal structure of T22, highlights the differences between this interaction and those of classical MHC molecules and alpha beta T cells. (C) 2000 Elsevier Science Ltd. All rights reserved.
引用
收藏
页码:R282 / R285
页数:4
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