A recent study describes direct binding between a gamma delta T-cell receptor and its ligand, T22, a non-classical class I major histocompatibility complex (MHC) molecule. A companion study, solving the crystal structure of T22, highlights the differences between this interaction and those of classical MHC molecules and alpha beta T cells. (C) 2000 Elsevier Science Ltd. All rights reserved.
机构:
Univ N Carolina, Int Ctr Advancement Translat Sci, Chapel Hill, NC 27599 USA
Univ N Carolina, Dept Med, Div Infect Dis, Chapel Hill, NC 27599 USA
Univ N Carolina, Ctr AIDS Res, Chapel Hill, NC 27599 USAUniv N Carolina, Int Ctr Advancement Translat Sci, Chapel Hill, NC 27599 USA