Medicolegal Implications of Biphasic Anaphylaxis

被引：5

作者：

Da Broi, Ugo ^{[1
]}

Moreschi, Carlo ^{[1
]}

Marega, Giulia ^{[1
]}

Tse, Rexson ^{[2
,3
]}

Garland, Jack ^{[4
]}

Ondruschka, Benjamin ^{[5
]}

Palmiere, Cristian ^{[6
]}

机构：

[1] Univ Udine, Dept Med, Forens Med, Udine, Italy

[2] Univ Auckland, Sch Med, Fac Med & Hlth Sci, Auckland, New Zealand

[3] Auckland City Hosp, Dept Forens Pathol, LabPLUS, Auckland, New Zealand

[4] NSW Hlth Pathol, Forens & Analyt Sci Serv, Newcastle, NSW, Australia

[5] Univ Med Ctr Hamburg Eppendorf, Inst Legal Med, Hamburg, Germany

[6] Lausanne Univ Hosp, Univ Ctr Legal Med, CURML, Lausanne, Switzerland

来源：

AMERICAN JOURNAL OF FORENSIC MEDICINE AND PATHOLOGY | 2021年 / 42卷 / 02期

关键词：

biphasic anaphylaxis; postmortem diagnosis; forensic medicine; tryptase; biochemical marker; PLATELET-ACTIVATING-FACTOR; EMERGENCY-DEPARTMENT; CLINICAL PREDICTORS; PROTRACTED ANAPHYLAXIS; SYSTEMIC-ANAPHYLAXIS; ALLERGIC REACTIONS; BINDING EPITOPES; KOUNIS SYNDROME; CHILDREN; FOOD;

D O I：

10.1097/PAF.0000000000000621

中图分类号：

DF [法律]; D9 [法律]; R [医药、卫生];

学科分类号：

0301 ; 10 ;

摘要：

Biphasic anaphylaxis is an uncommon IgE-mediated condition whose pathophysiological mechanisms, risk factors, and predictive signs are not properly understood. Fortunately, the lethality of biphasic anaphylaxis, although probably underestimated, is low. Preventive clinical measures for biphasic anaphylaxis are neither standardized nor commonly applied. Furthermore, there are no laboratory protocols or anaphylactic markers to help identify the onset of biphasic anaphylaxis in clinical settings. The aim of this review is to highlight the medicolegal difficulties facing coroners and forensic pathologists in terms of the diagnosis and assessment of harm for victims and survivors of biphasic anaphylaxis.

引用

收藏

页码：109 / 117

页数：9

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