DEEPMIND'S AI PREDICTS STRUCTURES FOR A VAST TROVE OF PROTEINS

被引：29

作者：

Callaway, Ewen

机构：

来源：

NATURE | 2021年 / 595卷 / 7869期

关键词：

Proteomics; Structural biology; Machine learning;

D O I：

10.1038/d41586-021-02025-4

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

AlphaFold neural network produced a 'totally transformative' database of more than 350,000 structures from Homo sapiens and 20 model organisms. AlphaFold neural network produced a 'totally transformative' database of more than 350,000 structures from Homo sapiens and 20 model organisms.

引用

页码：635 / 635

页数：1

共 2 条

[1] Highly accurate protein structure prediction with AlphaFold [J].

Jumper, John ;

Evans, Richard ;

Pritzel, Alexander ;

Green, Tim ;

Figurnov, Michael ;

Ronneberger, Olaf ;

Tunyasuvunakool, Kathryn ;

Bates, Russ ;

Zidek, Augustin ;

Potapenko, Anna ;

Bridgland, Alex ;

Meyer, Clemens ;

Kohl, Simon A. A. ;

Ballard, Andrew J. ;

Cowie, Andrew ;

Romera-Paredes, Bernardino ;

Nikolov, Stanislav ;

Jain, Rishub ;

Adler, Jonas ;

Back, Trevor ;

Petersen, Stig ;

Reiman, David ;

Clancy, Ellen ;

Zielinski, Michal ;

Steinegger, Martin ;

Pacholska, Michalina ;

Berghammer, Tamas ;

Bodenstein, Sebastian ;

Silver, David ;

Vinyals, Oriol ;

Senior, Andrew W. ;

Kavukcuoglu, Koray ;

Kohli, Pushmeet ;

Hassabis, Demis .

NATURE, 2021, 596 (7873) :583-+

[2] Highly accurate protein structure prediction for the human proteome [J].