Treatment of lymphocytic hypophysitis by high-dose methylprednisolone pulse therapy

被引：45

作者：

Yamagami, K ^{[1
]}

Yoshioka, K ^{[1
]}

Sakai, H ^{[1
]}

Fukumoto, M ^{[1
]}

Yamakita, T ^{[1
]}

Hosoi, M ^{[1
]}

Ishii, T ^{[1
]}

Sato, T ^{[1
]}

Tanaka, S ^{[1
]}

Fujii, S ^{[1
]}

机构：

[1] Osaka City Gen Hosp, Dept Internal Med, Osaka 5340021, Japan

来源：

INTERNAL MEDICINE | 2003年 / 42卷 / 02期

关键词：

lymphocytic hypophysitis; high dose methylprednisolone; pulse therapy; pituitary mass; visual disturbance; magnetic resonance imaging;

D O I：

10.2169/internalmedicine.42.168

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

A 26-year-old woman 3 months post-partum was admitted to our hospital suffering from gross visual disturbance. Magnetic resonance imaging (MRI) revealed a pituitary mass, extending into the suprasellar cistern, with intense gadolinium enhancement. Lymphocytic hypophysitis (LHy) was suspected, and the patient received high dose methylprednisolone pulse therapy (HDMPT). Her visual disturbance was dramatically ameliorated on the first day following initiation of HDMPT, and MRI revealed marked mass reduction. Her pituitary function recovered 6 months after therapy. This case report suggests that HDMPT proved effective for mass reduction of severe LHy and could obviate the need for a useless surgery.

引用

页码：168 / 173

页数：6

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