Melt/solid polycondensation of glycolic acid to obtain high-molecular-weight poly(glycolic acid)

被引：92

作者：

Takahashi, K ^{[1
]}

Taniguchi, I ^{[1
]}

Miyamoto, M ^{[1
]}

Kimura, Y ^{[1
]}

机构：

[1] Kyoto Inst Technol, Dept Polymer Sci & Engn, Sakyo Ku, Kyoto 6068585, Japan

来源：

POLYMER | 2000年 / 41卷 / 24期

关键词：

polymer synthesis; poly(glycolic acid); polycondensation;

D O I：

10.1016/S0032-3861(00)00282-2

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

Bulk polycondensation of glycolic acid (GA) was studied to obtain high-molecular-weight poly(glycolic acid) (PGA). At first, a solid oligocondensate was prepared by melt-polycondensation of GA at 190 degrees C, and then it was subjected to solid-state polycondensation at the same temperature to increase the molecular weight. After the catalyst screening, zinc acetate dihydrate was discovered to be the best catalyst. The weight-average molecular weight of PGA reached 91,000, which was at the same level with that of PGA prepared by the conventional ring-opening polymerization of glycolide. This process can afford a facile route to large-scale synthesis of PGA. (C) 2000 Elsevier Science Ltd. Ail rights reserved.

引用

页码：8725 / 8728

页数：4

共 11 条

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