Understanding Frailty in Cancer Patients

被引:40
作者
Baijal, Pooja [1 ]
Periyakoil, Vyjeyanthi [1 ]
机构
[1] Stanford Hosp & Clin, Palo Alto, CA 94305 USA
关键词
Frailty; older adults; cancer; geriatric assessment; COMPREHENSIVE GERIATRIC ASSESSMENT; QUALITY-OF-LIFE; BREAST-CANCER; ELDERLY-PATIENTS; SOCIAL SUPPORT; OLDER PATIENTS; NUTRITIONAL-STATUS; PREDICT MORTALITY; PROSTATE-CANCER; PREVALENCE;
D O I
10.1097/PPO.0000000000000068
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
As population ages, the number of older adults with cancer is increasing rapidly. Chronological age per se is a poor guide for an oncologist to determine tolerance to cancer treatment. Older adults have been underrepresented in cancer clinical trials, leading to paucity of guidelines to meet the treatment challenges in this population. To evaluate an older adult with cancer, oncologists must understand age-related changes and identify the subset of population who is vulnerable and at risk of cancer treatment toxicity. Comprehensive geriatric assessments focusing on functional status, multimorbidity, nutritional status, cognitive impairment, and psychosocial support help recognize heterogeneity among older adults, leading to individualized approaches toward cancer treatment. The treatment decisions need to be made in collaboration with the patient's values and preferences.
引用
收藏
页码:358 / 366
页数:9
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