Management of high-risk populations with locally advanced prostate cancer

被引:28
作者
Khan, MA [1 ]
Partin, AW [1 ]
机构
[1] Johns Hopkins Univ, Sch Med, James Buchanan Brady Urol Inst, Baltimore, MD USA
关键词
locally advanced prostate cancer; risk factors; management;
D O I
10.1634/theoncologist.8-3-259
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Prostate cancer that extends beyond the confines of the prostatic gland on clinical and/or radiographic assessment, without evidence of lymph node or distant metastases, is regarded as locally advanced. The locally advanced prostate cancer patient population consists of a heterogeneous group of men, some of whom have tumors that may be amenable to primary curative intent with local definitive therapy associated with acceptable long-term cancer control rates. In order to optimally manage this group of patients, it is important to be able to recognize who is at a high risk of tumor recurrence after primary local therapy. In this brief review, we discuss the factors that contribute to the prediction of high risk in populations with locally advanced disease and the treatment options available.
引用
收藏
页码:259 / 269
页数:11
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