Corrosion resistance of Ti-Si-N coatings in blood and cytocompatibility with vascular endothelial cells

被引：5
作者：
Zhang, Ming [1 ,2 ]
Gao, Ang [2 ]
Ma, Shengli [1 ]
Xu, Kewei [1 ]
Chu, Paul K. [2 ]
机构：
[1] Xi An Jiao Tong Univ, State Key Lab Mech Behav Mat, Xian 710049, Peoples R China
[2] City Univ Hong Kong, Dept Phys & Mat Sci, Tat Chee Ave, Kowloon, Hong Kong, Peoples R China
来源：
VACUUM | 2016年 / 128卷
关键词：
Ti-Si-N coatings; Corrosion resistance; Cell proliferation; Hemocompatibility; SUPERHARD NANOCOMPOSITE COATINGS; SILICON-NITRIDE; BIAS VOLTAGE; MECHANICAL-PROPERTIES; TITANIUM; HEMOCOMPATIBILITY; BIOCOMPATIBILITY; COMPOSITE; SURFACES; BEHAVIOR;
D O I：
10.1016/j.vacuum.2016.03.009
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Ti-Si-N coatings are deposited on titanium alloy by arc-enhanced magnetron sputtering at different negative bias voltages and their corrosion resistance in blood, effects on platelet activation, endothelial cell functions are studied. The Ti-Si-N coatings are made up of crystalline TiN and amorphous Si3N4 phases and show better corrosion resistance compared with titanium alloy. Reduced platelet receptor activation is observed on the Ti-Si-N coatings and that deposited at -100 V shows the longest clotting time and smallest platelet activation. Ti-Si-N coatings also enhance the endothelial cell proliferation and spreading as well as the endothelial nitric oxide synthase (eNOS) expression. (C) 2016 Elsevier Ltd. All rights reserved.
引用
收藏
页码：45 / 55
页数：11
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