Detecting freezing of gait with a tri-axial accelerometer in Parkinson's disease patients

被引:91
作者
Ahlrichs, Claas [1 ]
Sama, Albert [3 ]
Lawo, Michael [2 ]
Cabestany, Joan [3 ]
Rodriguez-Martin, Daniel [3 ]
Perez-Lopez, Carlos [3 ]
Sweeney, Dean [4 ]
Quinlan, Leo R. [4 ]
Laighin, Gearoid O. [4 ]
Counihan, Timothy [5 ]
Browne, Patrick [5 ]
Hadas, Lewy [6 ]
Vainstein, Gabriel [6 ]
Costa, Alberto [7 ,9 ]
Annicchiarico, Roberta [7 ]
Alcaine, Sheila [8 ]
Mestre, Berta [8 ]
Quispe, Paola [8 ]
Bayes, Angels [8 ]
Rodriguez-Molinero, Alejandro [4 ]
机构
[1] Neusta Mobile Solut GmbH NMS, Konsul Smidt Str 24, D-28217 Bremen, Germany
[2] Univ Bremen, Inst Artificial Intelligence AGKI, D-28359 Bremen, Germany
[3] Univ Politecn Cataluna, Tech Res Ctr Dependency Care & Autonomous Living, Vilanova I La Geltr, Spain
[4] NUI Galway, Dept Elect & Elect Engn, Galway, Ireland
[5] NUI Galway, Sch Med, Galway, Ireland
[6] Maccabi Healthcare Serv, Tel Aviv, Israel
[7] IRCCS Fdn Santa Lucia, Rome, Italy
[8] Unidad Parkinson & Trastornos Movimiento UParkins, Barcelona, Spain
[9] Niccolo Cusano Univ Rome, Rome, Italy
关键词
Parkinson's disease; Freezing of Gait; Machine learning; Support vector machines; DIAGNOSIS; SYMPTOMS; MODELS;
D O I
10.1007/s11517-015-1395-3
中图分类号
TP39 [计算机的应用];
学科分类号
081203 ; 0835 ;
摘要
Freezing of gait (FOG) is a common motor symptom of Parkinson's disease (PD), which presents itself as an inability to initiate or continue gait. This paper presents a method to monitor FOG episodes based only on acceleration measurements obtained from a waist-worn device. Three approximations of this method are tested. Initially, FOG is directly detected by a support vector machine (SVM). Then, classifier's outputs are aggregated over time to determine a confidence value, which is used for the final classification of freezing (i.e., second and third approach). All variations are trained with signals of 15 patients and evaluated with signals from another 5 patients. Using a linear SVM kernel, the third approach provides 98.7 % accuracy and a geometric mean of 96.1 %. Moreover, it is investigated whether frequency features are enough to reliably detect FOG. Results show that these features allow the method to detect FOG with accuracies above 90 % and that frequency features enable a reliable monitoring of FOG by using simply a waist sensor.
引用
收藏
页码:223 / 233
页数:11
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