Bovine Leukemia virus titer and leukocyte population associated with mastitis in periparturient dairy cows

被引:0
作者
Kakinuma, Seiichi [1 ]
Maeda, Yousuke [2 ]
Ohtsuka, Hiromichi [2 ]
Konnai, Satoru [3 ]
Oikawa, Masa-aki [2 ]
机构
[1] Kakinuma Vet Hosp, Honjou 3670212, Japan
[2] Kitasato Univ, Sch Vet Med, Towada, Aomori 0348628, Japan
[3] Hokkaido Univ, Grad Sch Vet Med, Dept Dis Control, Sapporo, Hokkaido 0600818, Japan
来源
INTERNATIONAL JOURNAL OF APPLIED RESEARCH IN VETERINARY MEDICINE | 2014年 / 12卷 / 03期
关键词
bovine leukemia virus; CD4(+); CD8(+) and CD335(+) cells; leukocyte population; mastitis; periperturient; BLOOD MONONUCLEAR-CELLS; PERIPHERAL-BLOOD; NATURAL TRANSMISSION; INFECTION; CATTLE; SUBPOPULATIONS; BLV;
D O I
暂无
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
We examined the association of postpartum mastitis with virus titer and leukocyte population of Bovine leukemia virus (BLV) infected cows monitoring sixteen BLV infected cows for 3 months after calving. Five cows developed mastitis (Mastitis Group) and 11 cows without mastitis served as a control group (Control Group). Flow cytometric analysis of peripheral blood leukocyte population exhibited higher number of MHC class-II+CD14- cells in both groups without significant difference between groups. CD3(+), CD4(+), CDS+, and CD335(+) cell numbers in Mastitis Group were lower than the Control Group around the time of calving, but significant difference was observed only for CD335(+) cell number. Virus titer in blood significantly increased in Mastitis Group after calving compared to pre-calving titer. These results suggested that lower number of peripheral blood T cells in Mastitis Group cows might have heightened susceptibility to mastitis. In addition, Mastitis Group cows had higher peripheral blood BLV, which might have spread to surroundings.
引用
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页码:239 / 244
页数:6
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