Vanadium Complex Derived from N′-(3-Bromo-5-chloro-2-hydroxybenzylidene)-3-methylbenzohydrazide: Synthesis, Crystal Structure and Biological Activity

被引：0
|
作者：
Han, Zhen-Quan [1 ]
Han, Shuang [2 ]
Wang, Yuan [3 ]
机构：
[1] Qiqihar Univ, Appl Tech Coll, Qiqihar 161006, Peoples R China
[2] Qiqihar Univ, Coll Chem & Chem Engn, Qiqihar 161006, Peoples R China
[3] Qiqihar Environm Monitoring Cent Stn, Qiqihar 161005, Peoples R China
来源：
ACTA CHIMICA SLOVENICA | 2016年 / 63卷 / 01期
关键词：
Hydrazone ligand; Vanadium complex; Crystal structure; Insulin-like activity; COORDINATED OXOVANADIUM(V) COMPLEX; INSULIN-LIKE ACTIVITY; UREASE INHIBITION; DERIVATIVES; AROYLHYDRAZONE; REDUCTION; COMPOUND; LIGANDS; RATS;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Reaction of VO(acac)(2) with N'-(3-bromo-5-chloro-2-hydroxybenzylidene)-3-methylbenzohydrazide (H2L) in methanol afforded a new mononuclear vanadium(V) complex, [VOL(OMe)(MeOH)]. Structure of the complex has been characterized by physico-chemical methods and single-crystal X-ray diffraction. The complex crystallizes as the monoclinic space group P2(1)/c, with unit cell dimensions a = 13.1345(10) angstrom, b = 18.6279(14) angstrom, c = 7.8983(8) angstrom, beta = 90.248(2)degrees, V = 1932.4(3) angstrom(3), Z = 4, R-1 = 0.0963, wR(2) = 0.2213, S = 1.113. X-ray analysis indicated that the V atom in the complex is in octahedral coordination. The insulin-like activity of the complex was studied, which can stimulate glucose uptake with 2-DOG uptake value of 0.81 nmol / 3 min.
引用
收藏
页码：200 / 203
页数：4
相关论文
共 50 条
  • [11] A Maltolato-Coordinated Oxovanadium(V) Complex Derived from N′-(3-Bromo-5-chloro-2-hydroxybenzylidene)-3-hydroxyl-4-methoxybenzohydrazide: Synthesis, Crystal Structure, and Insulin-Enhancing Activity
    Li Lu-Xi
    Sun Ying
    Xie Qing
    Sun Yu-Bing
    Li Kun-Hua
    Li Wei
    You Zhong-Lu
    CHINESE JOURNAL OF INORGANIC CHEMISTRY, 2016, 32 (02) : 369 - 376
  • [12] SYNTHESIS, X-RAY CRYSTAL STRUCTURES AND CATALYTIC EPOXIDATION OF OXIDOVANADIUM(V) COMPLEXES DERIVED FROM N'-(5-CHLORO-2-HYDROXYBENZYLIDENE)-3-METHYLBENZOHYDRAZIDE
    Zou, D. -h.
    Liang, M.
    Chen, W.
    JOURNAL OF STRUCTURAL CHEMISTRY, 2024, 65 (10) : 1994 - 2003
  • [13] 2′-(3-bromo-5-chloro-2-hydroxybenzylidene) isonicotinohydrazide methanol solvate
    Tang, Chun-Bao
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2008, 64 : O1381 - U1259
  • [14] N′-(3-Bromo-5-chloro-2-hydroxybenzylidene)-2-chlorobenzohydrazide methanol solvate
    Weng, Qianfeng
    Zou, Cunjie
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O801 - U2394
  • [15] Crystal structure and insulin-like activity of a vanadium complex derived from N′-(3,5-dichloro-2-hydroxybenzylidene)-2-methylbenzohydrazide
    Han, S.
    Wang, Y.
    JOURNAL OF STRUCTURAL CHEMISTRY, 2016, 56 (06) : 1188 - 1192
  • [16] Synthesis, characterization, crystal structures, and antimicrobial activity of cobalt(II) and iron(III) complexes derived from N'-(2-hydroxybenzylidene)-3-methylbenzohydrazide
    T. Yang
    F. Niu
    L. X. Li
    Z. N. Xia
    Y. Zhang
    Z. L. You
    Russian Journal of Coordination Chemistry, 2016, 42 : 402 - 409
  • [17] Crystal structure and insulin-like activity of a vanadium complex derived from N′-(3,5-dichloro-2-hydroxybenzylidene)-2-methylbenzohydrazide
    S. Han
    Y. Wang
    Journal of Structural Chemistry, 2015, 56 : 1188 - 1192
  • [18] Synthesis, Characterization, Crystal Structures, and Antimicrobial Activity of Cobalt(II) and Iron(III) Complexes Derived from N′-(2-Hydroxybenzylidene)-3-Methylbenzohydrazide
    Yang, T.
    Niu, F.
    Li, L. X.
    Xia, Z. N.
    Zhang, Y.
    You, Z. L.
    RUSSIAN JOURNAL OF COORDINATION CHEMISTRY, 2016, 42 (06) : 402 - 409
  • [19] N′-(3-Bromo-5-chloro-2-hydroxybenzylidene)-3,4,5-trihydroxybenzohydrazide methanol solvate
    Alhadi, Abeer A. Abdul
    Ali, Hapipah Mohd.
    Ng, Seik Weng
    ACTA CRYSTALLOGRAPHICA SECTION E-STRUCTURE REPORTS ONLINE, 2009, 65 : O909 - U3288
  • [20] Vanadium(V) Complexes Derived from N'-(3-Bromo-2-hydroxybenzylidene)-2-methylbenzohydrazide and N'-(3-Bromo-2-hydroxybenzylidene)-2-methoxybenzohydrazide: Syntheses and Structures
    Qian, Shao-Song
    Han, Xiao
    Ye, Yu-Ting
    You, Zhonglu
    Zhu, Hai-Liang
    SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY, 2016, 46 (08) : 1124 - 1128
12345