Identification of antioxidant compound from Asparagus racemosus

被引:54
|
作者
Wiboonpun, N [1 ]
Phuwapraisirisan, P [1 ]
Tip-Pyang, S [1 ]
机构
[1] Chulalongkorn Univ, Fac Sci, Dept Chem, Nat Res Unit, Bangkok 10330, Thailand
关键词
Asparagus racemosus; antioxidant; benzofuran; racemofuran;
D O I
10.1002/ptr.1526
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
Roots of Asparagus racemosus were found to possess antioxidant property. DPPH autography-directed separation resulted in the identification of a new antioxidant compound named racemofuran (3) along with two known compounds asparagamine A (1) and racemosol (2). The structure of 3 was fully characterized by spectroscopic data (UV, MS, H-1 NMR, C-13 NMR, and 2D NMR). Racemofuran revealed antioxidant property against DPPH with IC50 value of 130 muM. Copyright (C) 2004 John Wiley Sons, Ltd.
引用
收藏
页码:771 / 773
页数:3
相关论文
共 50 条
  • [1] Bioactive compound, polyphenol content, and antioxidant activity of Asparagus racemosus Linn. root extract
    Oli, Sheetal
    Chauhan, Harsh Kumar
    Bisht, Anil Kumar
    Agnihotri, Saumya
    Dobhal, Preeti
    NATURAL PRODUCT RESEARCH, 2024, 38 (22) : 4065 - 4070
  • [2] Steroidal Saponins from Asparagus racemosus
    Sharma, Upendra
    Saini, Rikki
    Kumar, Bobita Neeraj
    Singh, Bikram
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2009, 57 (08) : 890 - 893
  • [3] Cognition improving and antioxidant effects of asparagus racemosus willd in mice
    Joshi, H.
    Parle, M.
    INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY, 2012, 15 : 204 - 204
  • [4] Phytochemical Investigation and Evaluation of Antibacterial and Antioxidant Potentials of Asparagus racemosus
    Karmakar, U. K.
    Biswas, S. K.
    Chowdhury, A.
    Raihan, S. Z.
    Akbar, M. A.
    Muhit, M. A.
    Mowla, R.
    INTERNATIONAL JOURNAL OF PHARMACOLOGY, 2012, 8 (01) : 53 - 57
  • [5] Steroidal saponins from the fruits of Asparagus racemosus
    Mandal, Debayan
    Banerjee, Sukdeb
    Mondal, Nirup B.
    Chakravarty, Ajit K.
    Sahu, Niranjan P.
    PHYTOCHEMISTRY, 2006, 67 (13) : 1316 - 1321
  • [6] A new isoflavone from the roots of Asparagus racemosus
    Saxena, VK
    Chourasia, S
    FITOTERAPIA, 2001, 72 (03) : 307 - 309
  • [7] Antioxidant and hepatoprotective action of Asparagus racemosus Willd. root extracts
    Acharya, S. R.
    Acharya, N. S.
    Bhangale, J. O.
    Shah, S. K.
    Pandya, S. S.
    INDIAN JOURNAL OF EXPERIMENTAL BIOLOGY, 2012, 50 (11) : 795 - 801
  • [8] Steroidal saponins from the roots of Asparagus racemosus
    Hayes, Patricia Y.
    Jahidin, Aisyah H.
    Lehmann, Reg
    Penman, Kerry
    Kitching, William
    De Voss, James J.
    PHYTOCHEMISTRY, 2008, 69 (03) : 796 - 804
  • [9] Antiglycation activity of β-glucogallin from Asparagus racemosus
    Ahmad, Shadab
    Pandey, Alka Raj
    Singh, Suriya Pratap
    Singh, Sushmita
    Sashidhara, Koneni, V
    Tamrakar, Akhilesh K.
    NATURAL PRODUCT RESEARCH, 2022, 36 (24) : 6329 - 6335
  • [10] Evaluation of antioxidant activities of different extracts of roots of Asparagus Racemosus willd
    Acharya, Sanjeev Rameshchandra
    Acharya, Niyati S.
    Shah, Samir K.
    Pandya, Saurabh S.
    FREE RADICAL BIOLOGY AND MEDICINE, 2006, 41 : S19 - S19