Acceleration of Bone Regeneration Using Low Intensity Pulsed Ultrasound

被引:0
作者
Kang, Kyung Lhi [1 ]
Chung, Jong Hyuk [1 ,2 ]
机构
[1] Kyung Hee Univ, Dept Periodont, Sch Dent, Seoul 130702, South Korea
[2] Kyung Hee Univ, Inst Oral Biol, Sch Dent, Seoul 130702, South Korea
关键词
LIPUS(low-intensity pulsed ultrasound); bone regeneration; mechanical stimulus; MESENCHYMAL STEM-CELLS; AGGRECAN GENE-EXPRESSION; THERAPEUTIC ULTRASOUND; HUMAN OSTEOBLASTS; FRACTURE MODEL; IN-VITRO; DISTRACTION OSTEOGENESIS; NITRIC-OXIDE; RAT; STIMULATION;
D O I
暂无
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Ultrasound has been Studied for stimulation of bone fracture healing for a long lime. After many researches of high and low intensity ultrasound, researchers became focused on low-intensity pulsed ultrasound (LIPUS) recently. One of the effects of LIPUS is acceleration of bone regeneration without unfavorable results such as bone necrosis and fibrous or delayed healing, but the exact mechanism is not elucidated yet. The purpose of this feature article is to review researches of LIPUS up to now and to know the trend and future research focuses.
引用
收藏
页码:1183 / 1190
页数:8
相关论文
共 68 条
[1]   EFFECT OF ULTRASOUND ON TIBIA OF YOUNG RAT [J].
ABRAMOVICH, A .
JOURNAL OF DENTAL RESEARCH, 1970, 49 (05) :1182-+
[2]   ULTRASONIC ENERGY AND SURGICALLY PRODUCED DEFECTS IN BONE [J].
ARDAN, NI ;
JANES, JM ;
HERRICK, JF .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1957, 39 (02) :394-402
[3]   Low-intensity pulsed ultrasound accelerates rat femoral fracture healing by acting on the various cellular reactions in the fracture callus [J].
Azuma, Y ;
Ito, M ;
Harada, Y ;
Takagi, H ;
Ohta, T ;
Jingushi, S .
JOURNAL OF BONE AND MINERAL RESEARCH, 2001, 16 (04) :671-680
[4]  
BENDER L F, 1954, Arch Phys Med Rehabil, V35, P555
[5]  
BUCHTALA V, 1950, DIA MED, V30, P2944
[6]   Study of thermal effects of ultrasound stimulation on fracture healing [J].
Chang, WHS ;
Sun, JS ;
Chang, SP ;
Lin, JC .
BIOELECTROMAGNETICS, 2002, 23 (04) :256-263
[7]   ULTRASOUND-INDUCED CHANGES IN RATES OF INFLUX AND EFFLUX OF POTASSIUM-IONS IN RAT THYMOCYTES INVITRO [J].
CHAPMAN, IV ;
MACNALLY, NA ;
TUCKER, S .
ULTRASOUND IN MEDICINE AND BIOLOGY, 1980, 6 (01) :47-&
[8]   Pertussis toxin-sensitive Gαi protein and ERK-dependent pathways mediate ultrasound promotion of osteogenic transcription in human osteoblasts [J].
Chen, YJ ;
Wang, CJ ;
Yang, KD ;
Chang, PR ;
Huang, HC ;
Sun, YC ;
Wang, FS .
FEBS LETTERS, 2003, 554 (1-2) :154-158
[9]   The enhancement of bone regeneration by ultrasound [J].
Claes, Lutz ;
Willie, Bettina .
PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, 2007, 93 (1-3) :384-398
[10]  
Cook SD, 1997, CLIN ORTHOP RELAT R, P198