Copper-catalyzed electrophilic amination of functionalized diarylzinc reagents

被引：80
作者：
Berman, AM [1 ]
Johnson, JS [1 ]
机构：
[1] Univ N Carolina, Dept Chem, Chapel Hill, NC 27599 USA
来源：
JOURNAL OF ORGANIC CHEMISTRY | 2005年 / 70卷 / 01期
关键词：
D O I：
10.1021/jo048168g
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The copper-catalyzed electrophilic amination of functionalized diarylzinc reagents with O-acyl hydroxylamines allows for the preparation of functionalized tertiary arylamines in high yields, and is noteworthy for the mild reaction conditions employed. The functionalized diarylzinc reagents were prepared via an iodine/magnesium exchange of the corresponding aryl iodide followed by transmetalation of the resultant Grignard species with ZnCl2.
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页码：364 / 366
页数：3
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