In vitro effectiveness of linezolid in brucellosis

被引:0
作者
Sayiner, Hakan Sezgin [1 ]
Akgun, Sadik [2 ]
机构
[1] Adiyaman Univ, Fac Med, Dept Infect Dis & Clin Microbiol, Adiyaman, Turkey
[2] Adiyaman Univ, Fac Med, Dept Med Microbiol, Adiyaman, Turkey
来源
BIOMEDICAL RESEARCH-INDIA | 2017年 / 28卷 / 14期
关键词
Linezolid; Brucellosis; Oxazolidinone; DOXYCYCLINE-RIFAMPIN; TUBERCULOSIS; TIGECYCLINE; MELITENSIS; RESISTANT;
D O I
暂无
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Antibiotic sensitivities for Linezolid of 20 strains that reported as Brucella melitensis in blood cultures between 2014 and 2016 were evaluated by disc diffusion and E-test methods. According to the disc diffusion method results, 20 Brucella melitensis strains had >= 25 mm of antibiotic sensitivity zones. E-test measurements revealed that MIC values were between 1.5 and 6 mu g. Linezolid can be an alternative when the treatment of Brucellosis prolongs and becomes difficult due to recurrences and relapses, or when it becomes complicated in cases like spondylodiscitis or neurobrucellosis.
引用
收藏
页码:6234 / 6236
页数:3
相关论文
共 22 条
[1]   QUINOLONES IN TREATMENT OF HUMAN BRUCELLOSIS - COMPARATIVE TRIAL OF OFLOXACIN-RIFAMPIN VERSUS DOXYCYCLINE-RIFAMPIN [J].
AKOVA, M ;
UZUN, O ;
AKALIN, HE ;
HAYRAN, M ;
UNAL, S ;
GUR, D .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 1993, 37 (09) :1831-1834
[2]   In vitro activities of linezolid against clinical isolates of Mycobacterium tuberculosis that are susceptible or resistant to first-line antituberculous drugs [J].
Alcalá, L ;
Ruiz-Serrano, MJ ;
Turégano, CPF ;
Garcia de Viedma, D ;
Díaz-Infantes, M ;
Marín-Arriaza, M ;
Bouza, E .
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2003, 47 (01) :416-417
[3]  
Alkan BM, 2004, J PMR SCI, V7, P99
[4]  
Alptekin N, 2003, TURKIYE KLINIKLERI F, V3, P97
[5]  
Altun B, 2009, TRAK UNIV TIP FAK DE, V26, P261
[6]  
Cevik MA, 2003, ANKEM DERG
[7]   Experience with linezolid for the treatment of nocardiosis in organ transplant recipients [J].
De la Cruz, Oveimar ;
Minces, Lucio R. ;
Silveira, Fernanda P. .
JOURNAL OF INFECTION, 2015, 70 (01) :44-51
[8]   In vitro activity of Brucella melitensis isolates to various antimicrobials in Turkey [J].
Denk, Affan ;
Demirdag, Kutbettin ;
Kalkan, Ahmet ;
Ozden, Mehmet ;
Cetinkaya, Burhan ;
Kilic, Suleyman S. .
INFECTIOUS DISEASES, 2015, 47 (06) :364-369
[9]   Oxazolidinones - A review [J].
Diekema, DJ ;
Jones, RN .
DRUGS, 2000, 59 (01) :7-16
[10]   Linezolid for the treatment of multidrug-resistant tuberculosis [J].
Fortún, J ;
Martín-Dávila, P ;
Navas, E ;
Pérez-Elías, MJ ;
Cobo, J ;
Tato, M ;
De la Pedrosa, EGG ;
Gómez-Mampaso, E ;
Moreno, S .
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY, 2005, 56 (01) :180-185