Posterior Reversible Encephalopathy Syndrome After Intravitreal Bevacizumab Injection in Patient with Choroidal Neovascular Membrane Secondary to Age-Related Maculopathy

被引:13
作者
Artunay, Ozgur [1 ]
Yuzbasioglu, Erdal [1 ]
Rasier, Rifat [1 ]
Sengul, Alper [1 ]
Bahcecioglu, Halil [1 ]
机构
[1] Istanbul Bilim Univ, Dept Ophthalmol, Istanbul, Turkey
关键词
MACULAR DEGENERATION; AVASTIN;
D O I
10.1089/jop.2009.0148
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
The posterior reversible encephalopathy syndrome (PRES), a complex of cerebral disorders including headache, seizures, visual disturbances, is associated with a variety of conditions in which blood pressure rises acutely. Arterial hypertension can occur in systemic administration of bevacizumab. A few cases of systemic injection of bevazicumab-induced PRES have been reported. In this article, we first report on a patient who developed PRES following intravitreal bevazicumab.
引用
收藏
页码:301 / 303
页数:3
相关论文
共 8 条
[1]   Pharmacokinetics of intravitreal bevackumab (avastin) [J].
Bakri, Sophie J. ;
Snyder, Melissa R. ;
Reid, Joel M. ;
Pulido, Jose S. ;
Singh, Ravinder J. .
OPHTHALMOLOGY, 2007, 114 (05) :855-859
[2]   Reversible posterior leukoencephalopathy syndrome associated with bevacizumab/doxorubicin regimen [J].
Burki, Franck ;
Badie, Kattalin ;
Bartoli, Philippe ;
Bernard, Pascale ;
Montastruc, Jean Louis ;
Bagheri, Haleh .
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2008, 65 (05) :793-794
[3]   Intravitreal bevacizumab (avastin) treatment of neovascular age-related macular degeneration [J].
Emerson, M. Vaughn ;
Lauer, Andreas K. ;
Flaxel, Christina J. ;
Wilson, David J. ;
Francis, Peter J. ;
Stout, J. Timothy ;
Emerson, Geoffrey G. ;
Schlesinger, Thomas K. ;
Nolte, Susan K. ;
Klein, Michael L. .
RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, 2007, 27 (04) :439-444
[4]   The International Intravitreal Bevacizumab Safety Survey: using the Internet to assess drug safety worldwide [J].
Fung, A. E. ;
Rosenfeld, P. J. ;
Reichel, E. .
BRITISH JOURNAL OF OPHTHALMOLOGY, 2006, 90 (11) :1344-1349
[5]  
OCZAN C, 2006, NEW ENGL J MED, V9, P980
[6]   The effect of intravitreal bevacizumab (avastin) administration on systemic hypertension [J].
Rasier, R. ;
Artunay, O. ;
Yuzbasioglu, E. ;
Sengul, A. ;
Bahcecioglu, H. .
EYE, 2009, 23 (08) :1714-1718
[7]   Optical coherence tomography findings after an intravitreal injection of bevacizumab (Avastin®) for neovascular age-related macular degeneration [J].
Rosenfeld, PJ ;
Moshfeghi, AA ;
Puliafito, CA .
OPHTHALMIC SURGERY LASERS & IMAGING, 2005, 36 (04) :331-335
[8]   Direct evidence that the VEGF-specific antibody bevacizumab has antivascular effects in human rectal cancer [J].
Willett, CG ;
Boucher, Y ;
di Tomaso, E ;
Duda, DG ;
Munn, LL ;
Tong, RT ;
Chung, DC ;
Sahani, DV ;
Kalva, SP ;
Kozin, SV ;
Mino, M ;
Cohen, KS ;
Scadden, DT ;
Hartford, AC ;
Fischman, AJ ;
Clark, JW ;
Ryan, DP ;
Zhu, AX ;
Blaszkowsky, LS ;
Chen, HX ;
Shellito, PC ;
Lauwers, GY ;
Jain, RK .
NATURE MEDICINE, 2004, 10 (02) :145-147