Identification of a new HLA-B*40 variant, B*4035

被引：6
作者：
Voorter, CEM
Hepkema, BG
Lems, SPM
van den Berg-Loonen, EM
机构：
[1] Univ Hosp, Tissue Typing Lab, NL-6202 AZ Maastricht, Netherlands
[2] Univ Groningen Hosp, Groningen, Netherlands
来源：
TISSUE ANTIGENS | 2003年 / 61卷 / 01期
关键词：
HLA-B; sequence-based typing; B*4035; new allele;
D O I：
10.1034/j.1399-0039.2003.610109.x
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
In this report, the novel allele B*4035(1) is presented. The allele was identified in a Caucasian individual by sequence-based typing. B*4035 is identical to B*4002 in exon 2, but differs in exon 3 at position 463, where it has an A in stead of a C. This results in an amino acid change from arginine to serine at codon 131 of the mature protein. The haplotype carrying the B*4035 was A3 B*4035 Cw2 DR11 DQ3.
引用
收藏
页码：89 / 91
页数：3
相关论文
共 17 条
[1]   Nomenclature for factors of the HLA system, 1998 [J].
Bodmer, JG ;
Marsh, SGE ;
Albert, ED ;
Bodmer, WF ;
Bontrop, RE ;
Dupont, B ;
Erlich, HA ;
Hansen, JA ;
Mach, B ;
Mayr, WR ;
Parham, P ;
Petersdorf, EW ;
Sasazuki, T ;
Schreuder, GMT ;
Strominger, JL ;
Svejgaard, A ;
Terasaki, PI .
TISSUE ANTIGENS, 1999, 53 (04) :407-446
[2]   Dimorphic primers derived from intron I for use in the molecular typing of HLA-B alleles [J].
Cereb, N ;
Yang, SY .
TISSUE ANTIGENS, 1997, 50 (01) :74-76
[3]   Nucleotide sequences of MHC class I introns 1, 2, and 3 in humans and intron 2 in nonhuman primates [J].
Cereb, N ;
Kong, Y ;
Lee, S ;
Maye, P ;
Yang, SY .
TISSUE ANTIGENS, 1996, 47 (06) :498-511
[4]  
Dawkins R. L., 1980, HISTOCOMPATIBILITY T, P454
[5]   Generation of the HLA-B35, -B5, -B16, and B15 groups of alleles studied by intron 1 and 2 sequence analysis [J].
GomezCasado, E ;
VargasAlarcon, G ;
MartinezLaso, J ;
PerezBlas, M ;
Granados, J ;
Layrisse, Z ;
Montoya, F ;
Varela, P ;
ArnaizVillena, A .
IMMUNOGENETICS, 1997, 46 (06) :469-476
[6]  
HAMMOND MG, 1972, TISSUE ANTIGENS, V2, P389
[7]  
Marsh S. G. E., 2001, Tissue Antigens, V57, P236
[8]   Diversity of alleles encoding HLA-B40: Relative frequencies in United States populations and description of five novel alleles [J].
Pimtanothai, N ;
Rizzuto, GA ;
Slack, R ;
Steiner, NK ;
Kosman, CA ;
Jones, PF ;
Koester, R ;
Ng, J ;
Hartzman, RJ ;
Hurley, CK .
HUMAN IMMUNOLOGY, 2000, 61 (08) :808-+
[9]  
Raffoux C, 1997, HLA - GENETIC DIVERSITY OF HLA FUNCTIONAL AND MEDICAL IMPLICATION, PROCEEDINGS OF THE TWELFTH INTERNATIONAL HISTOCOMPATIBILITY WORKSHOP AND CONFERENCE (12TH IHWC), VOL I: WORKSHOP, P69
[10]   IMGT/HLA Database - a sequence database for the human major histocompatibility complex [J].
Robinson, J ;
Malik, A ;
Parham, P ;
Bodmer, JG ;
Marsh, SGE .
TISSUE ANTIGENS, 2000, 55 (03) :280-287
12