Characteristics, outcomes, and predictors of mortality at 3 months and 1 year in patients hospitalized for acute heart failure

被引:209
作者
Harjola, Veli-Pekka [1 ]
Follath, Ferenc [2 ]
Nieminen, Markku S. [3 ]
Brutsaert, Dirk [4 ]
Dickstein, Kenneth [5 ,6 ]
Drexler, Helmut [7 ]
Hochadel, Matthias [8 ]
Komajda, Michel [9 ,10 ]
Lopez-Sendon, Jose L. [11 ]
Ponikowski, Piotr [12 ]
Tavazzi, Luigi [13 ]
机构
[1] Univ Helsinki, Cent Hosp, Div Emergency Care, Dept Med, Helsinki 00029, Hus, Finland
[2] Univ Zurich Hosp, Dept Internal Med, Zurich, Switzerland
[3] Univ Helsinki, Cent Hosp, Div Cardiol, Dept Med, Helsinki 00029, Hus, Finland
[4] Univ Antwerp, Dept Cardiol, AZ Middelheim Hosp, B-2020 Antwerp, Belgium
[5] Stavanger Univ Hosp, Stavanger, Norway
[6] Univ Bergen, Inst Internal Med, Bergen, Norway
[7] MHH, Abt Kardiol Angiol, Zentrum Innere Med, Hannover, Germany
[8] Heidelberg Univ, Stiftung Inst Herzinfarktforsch, Ludwigshafen, Germany
[9] Univ Paris 06, Paris 6, France
[10] CHU Pitie Salpetriere, Dept Cardiol, Paris, France
[11] Hosp Univ La Paz, Dept Cardiol Planta 1, Madrid, Spain
[12] Mil Hosp, Dept Cardiol, Wroclaw, Poland
[13] GVM Hosp Care & Res, Cotignola, Italy
关键词
Acute heart failure; Multicentre study; Survival; Prognosis; Survey; QUALITY-OF-CARE; PROGNOSTIC IMPACT; SURVEY PROGRAM; POPULATION; DIAGNOSIS; REGISTRY; ROSUVASTATIN; GUIDELINES; ADMISSION; EUROPE;
D O I
10.1093/eurjhf/hfq002
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Acute heart failure (AHF) has a poor prognosis. We evaluated 3- and 12-month mortality in different clinical classes of AHF patients from 30 European countries who were included in the EuroHeart Failure Survey (EHFS) II. Follow-up data were available for 2981 AHF patients, of these 62% had a history of chronic HF. One-year mortality after discharge was lower in patients with de novo AHF when compared with acutely decompensated chronic HF (ADCHF), 16.4 vs. 23.2% (P < 0.001). Cardiogenic shock conferred the highest cumulative 1-year mortality (52.9%) as a result of in-hospital mortality of 39.3%. Long-term prognosis in decompensated AHF was also dismal. Hypertensive HF was associated with the lowest mortality (13.7% at 1 year). Age, prior myocardial infarction, creatinine level, and low plasma sodium were independently associated with mortality during the whole follow-up period. Diabetes, anaemia, and history of chronic HF were associated with worse and hypertension with better long-term survival. History of cerebrovascular disease was associated with worse short-term outcome. Early and late mortality differ between de novo AHF and ADCHF and between clinical classes of AHF. EHFS II identifies clinical risk markers and demonstrates the importance of a thorough characterization of AHF populations according to history and clinical presentation.
引用
收藏
页码:239 / 248
页数:10
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