Unusually Large Hysteresis of Temperature-Responsive Poly(N-ethyl-2-propionamidoacrylamide) Studied by Microcalorimetry and FT-IR

被引：18

作者：

Berber, Mohamed R. ^{[2
]}

Mori, Hironori ^{[2
]}

Hafez, Inas H. ^{[2
]}

Minagawa, Keiji ^{[2
]}

Tanaka, Masami ^{[3
]}

Niidome, Takuro ^{[4
,5
]}

Katayama, Yoshiki ^{[4
,5
]}

Maruyama, Atsushi ^{[6
]}

Hirano, Tomohiro ^{[2
]}

Maeda, Yasushi ^{[1
]}

Mori, Takeshi ^{[4
,5
]}

机构：

[1] Univ Fukui, Dept Appl Chem & Biotechnol, Fukui 9108507, Japan

[2] Univ Tokushima, Inst Sci & Technol, Div Life Syst, Tokushima 7708506, Japan

[3] Tokushima Bunri Univ, Fac Pharmaceut Sci, Tokushima 7708514, Japan

[4] Kyushu Univ, Dept Appl Chem, Nishi Ku, Fukuoka 8190395, Japan

[5] Kyushu Univ, Ctr Future Chem, Nishi Ku, Fukuoka 8190395, Japan

[6] Kyushu Univ, Inst Mat Chem & Engn, Nishi Ku, Fukuoka 8190395, Japan

来源：

JOURNAL OF PHYSICAL CHEMISTRY B | 2010年 / 114卷 / 23期

关键词：

PHASE-TRANSITION; MOLECULAR-WEIGHT; POLY(N-ISOPROPYLACRYLAMIDE) CHAINS; GLOBULE TRANSITION; AQUEOUS-SOLUTIONS; HYDRATION STATES; WATER; SPECTROSCOPY; POLY(N-ISOPROPYLMETHACRYLAMIDE); SUBSTITUENTS;

D O I：

10.1021/jp102681q

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

We reported here the full characterization of the hysteresis of the phase transition behavior of an aqueous solution of poly(N-ethyl-2-propionamidoacrylamide) (PNEPA), which has a unique alpha,alpha-disubstituted structure, by using microcalorimetry and FT-IR. Phase transition temperatures near the thermodynamic equilibrium were determined by extrapolating the scanning rate of the microcalorimetry to zero. The calculated hysteresis from the phase transition temperature was unusually very large (similar to 8 degrees C). FT-IR analysis indicated that the large hysteresis of PNEPA resulted from a coupling of intra-/intermonomeric unit hydrogen bonds, which is known to occur in a beta-sheet of proteins but has never been reported in temperature-responsive polymers. The effects of the molecular weight and polymer concentration on the hysteresis were studied by using fractionated PNEPAs and it was found that a low molecular weight and a low concentration enhanced the hysteresis.

引用

页码：7784 / 7790

页数：7

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