Red cell transfusion and the immune system

被引：46
作者：
Hart, S. [1 ]
Cserti-Gazdewich, C. N. [2 ]
McCluskey, S. A. [1 ]
机构：
[1] Toronto Gen Hosp, Univ Hlth Network, Dept Anaesthesia & Pain Management, Toronto, ON, Canada
[2] Toronto Gen Hosp, Univ Hlth Network, Dept Haematol, Toronto, ON, Canada
来源：
ANAESTHESIA | 2015年 / 70卷
关键词：
ACUTE LUNG INJURY; OUTCOMES FOLLOWING INSTITUTION; IGA-DEFICIENT DONORS; VERSUS-HOST-DISEASE; BLOOD-CELLS; UNIVERSAL LEUKOREDUCTION; SERIOUS HAZARDS; CLINICAL-OUTCOMES; ANTI-IGA; PRESTORAGE LEUKOREDUCTION;
D O I：
10.1111/anae.12892
中图分类号：
R614 [麻醉学];
学科分类号：
100217 ;
摘要：
Understanding the complex immunological consequences of red cell transfusion is essential if we are to use this valuable resource wisely and safely. The decision to transfuse red cells should be made after serious considerations of the associated risks and benefits. Immunological risks of transfusion include major incompatibility reactions and transfusion-related acute lung injury, while other immunological insults such as transfusion-related immunomodulation are relatively underappreciated. Red cell transfusions should be acknowledged as immunological exposures, with consequences weighed against expected benefits. This article reviews immunological consequences and the emerging evidence that may inform risk-benefit considerations in clinical practice.
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页数：12
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共 132 条
  • [21] Probiotic-associated high-titer anti-B in a group A platelet donor as a cause of severe hemolytic transfusion reactions
    Daniel-Johnson, Jennifer
    Leitman, Susan
    Klein, Harvey
    Alter, Harvey
    Lee-Stroka, Agnes
    Scheinberg, Phillip
    Pantin, Jeremy
    Quillen, Karen
    [J]. TRANSFUSION, 2009, 49 (09) : 1845 - 1849
  • [22] Functions of red cell surface proteins
    Daniels, G.
    [J]. VOX SANGUINIS, 2007, 93 (04) : 331 - 340
  • [23] The clinical significance of blood group antibodies
    Daniels, G
    Poole, J
    de Silva, M
    Callaghan, T
    MacLennan, S
    Smith, N
    [J]. TRANSFUSION MEDICINE, 2002, 12 (05) : 287 - 295
  • [24] International Society of Blood Transfusion Committee on Terminology for Red Blood Cell Surface Antigens: Macao report
    Daniels, G.
    Castilho, L.
    Flegel, W. A.
    Fletcher, A.
    Garratty, G.
    Levene, C.
    Lomas-Francis, C.
    Moulds, J. M.
    Moulds, J. J.
    Olsson, M. L.
    Overbeeke, M.
    Poole, J.
    Reid, M. E.
    Rouger, P.
    van der Schoot, E.
    Scott, M.
    Sistonen, P.
    Smart, E.
    Storry, J. R.
    Tani, Y.
    Yu, L-C.
    Wendel, S.
    Westhoff, C.
    Yahalom, V.
    Zelinski, T.
    [J]. VOX SANGUINIS, 2009, 96 (02) : 153 - 156
  • [25] Variants of RhD - current testing and clinical consequences
    Daniels, Geoff
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2013, 161 (04) : 461 - 470
  • [26] Blood groups: the past 50 years
    Daniels, Geoff
    Reid, Marion E.
    [J]. TRANSFUSION, 2010, 50 (02) : 281 - 289
  • [27] Perioperative fluid management in kidney transplantation: Is volume overload still mandatory for graft function?
    De Gasperi, A.
    Narcisi, S.
    Mazza, E.
    Bettinelli, L.
    Pavani, M.
    Perrone, L.
    Grugni, C.
    Corti, A.
    [J]. TRANSPLANTATION PROCEEDINGS, 2006, 38 (03) : 807 - 809
  • [28] The immunohematologic and patient safety benefits of a centralized transfusion database
    Delaney, Meghan
    Dinwiddie, Steve
    Nester, Theresa N.
    AuBuchon, James A.
    [J]. TRANSFUSION, 2013, 53 (04) : 771 - 776
  • [29] Prevalence of HLA sensitization in female apheresis donors
    Densmore, TL
    Goodnough, LT
    Ali, S
    Dynis, M
    Chaplin, H
    [J]. TRANSFUSION, 1999, 39 (01) : 103 - 106
  • [30] Domen RE, 2003, ARCH PATHOL LAB MED, V127, P316
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