Red cell transfusion and the immune system

被引:46
作者
Hart, S. [1 ]
Cserti-Gazdewich, C. N. [2 ]
McCluskey, S. A. [1 ]
机构
[1] Toronto Gen Hosp, Univ Hlth Network, Dept Anaesthesia & Pain Management, Toronto, ON, Canada
[2] Toronto Gen Hosp, Univ Hlth Network, Dept Haematol, Toronto, ON, Canada
关键词
ACUTE LUNG INJURY; OUTCOMES FOLLOWING INSTITUTION; IGA-DEFICIENT DONORS; VERSUS-HOST-DISEASE; BLOOD-CELLS; UNIVERSAL LEUKOREDUCTION; SERIOUS HAZARDS; CLINICAL-OUTCOMES; ANTI-IGA; PRESTORAGE LEUKOREDUCTION;
D O I
10.1111/anae.12892
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
Understanding the complex immunological consequences of red cell transfusion is essential if we are to use this valuable resource wisely and safely. The decision to transfuse red cells should be made after serious considerations of the associated risks and benefits. Immunological risks of transfusion include major incompatibility reactions and transfusion-related acute lung injury, while other immunological insults such as transfusion-related immunomodulation are relatively underappreciated. Red cell transfusions should be acknowledged as immunological exposures, with consequences weighed against expected benefits. This article reviews immunological consequences and the emerging evidence that may inform risk-benefit considerations in clinical practice.
引用
收藏
页数:12
相关论文
共 132 条
  • [1] Alves Vitor Mendonça, 2012, Rev. Bras. Hematol. Hemoter., V34, P206
  • [2] Storage time of allogeneic red blood cells is associated with risk of severe postoperative infection after coronary artery bypass grafting
    Andreasen, Jan Jesper
    Dethlefsen, Claus
    Modrau, Ivy S.
    Baech, John
    Schonheyder, Henrik C.
    Moeller, Jens K.
    Johnsen, Soren P.
    [J]. EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY, 2011, 39 (03) : 329 - 334
  • [3] [Anonymous], 2013, WORKING PARTY HAEMOV
  • [4] [Anonymous], 2006, COCHRANE DATABASE SY
  • [5] Passive transfer of peanut hypersensitivity by fresh frozen plasma
    Arnold, Donald M.
    Blajchman, Morris A.
    DiTomasso, Julie
    Kulczycki, Myron
    Keith, Paul K.
    [J]. ARCHIVES OF INTERNAL MEDICINE, 2007, 167 (08) : 853 - 854
  • [6] Azarfarin Rasoul, 2009, Middle East Journal of Anesthesiology, V20, P101
  • [7] What every physician should know about transfusion reactions
    Bakdash, Suzanne
    Yazer, Mark H.
    [J]. CANADIAN MEDICAL ASSOCIATION JOURNAL, 2007, 177 (02) : 141 - 147
  • [8] Hemovigilance: Clinical tolerance of solvent-detergent treated plasma
    Baudoux, E
    Margraff, U
    Coenen, A
    Jacobs, X
    Strivay, M
    Lungu, C
    Sondag-Thull, D
    [J]. VOX SANGUINIS, 1998, 74 : 237 - 239
  • [9] An association between decreased cardiopulmonary complications (transfusion-related acute lung injury and transfusion-associated circulatory overload) and implementation of universal leukoreduction of blood transfusions
    Blumberg, Neil
    Heal, Joanna M.
    Gettings, Kelly F.
    Phipps, Richard P.
    Masel, Debra
    Refaai, Majed A.
    Kirkley, Scott A.
    Fialkow, L. Benjamin
    [J]. TRANSFUSION, 2010, 50 (12) : 2738 - 2744
  • [10] Serious Hazards of Transfusion (SHOT) haemovigilance and progress is improving transfusion safety
    Bolton-Maggs, Paula H. B.
    Cohen, Hannah
    [J]. BRITISH JOURNAL OF HAEMATOLOGY, 2013, 163 (03) : 303 - 314