A near-infrared xanthene-based fluorescent probe for selective detection of hydrazine and its application in living cells

被引：18

作者：

Guo, Shao-Hua ^{[1
,2
]}

Leng, Tao-Hua ^{[3
]}

Wang, Kai ^{[1
,2
]}

Shen, Yong-Jia ^{[1
,2
]}

Wang, Cheng-Yun ^{[1
,2
]}

机构：

[1] East China Univ Sci & Technol, Sch Chem & Mol Engn, Key Lab Adv Mat, Shanghai 200237, Peoples R China

[2] East China Univ Sci & Technol, Sch Chem & Mol Engn, Inst Fine Chem, Shanghai 200237, Peoples R China

[3] Shanghai Inst Qual Inspect & Tech Res, Natl Food Qual Supervis & Inspect Ctr Shanghai, Shanghai, Peoples R China

来源：

SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY | 2019年 / 223卷

基金：

中国国家自然科学基金; 上海市自然科学基金;

关键词：

Near-infrared fluorescence; Hydrazine; Bioimaging; High selectivity; LARGE STOKES SHIFT; IN-VITRO; AQUEOUS-SOLUTION; A549; ACTIVITY; NAKED-EYE; NANOPARTICLES; GOLD; RED;

D O I：

10.1016/j.saa.2019.117344

中图分类号：

O433 [光谱学];

学科分类号：

0703 ; 070302 ;

摘要：

Developing fluorescent probes for selective determination of the toxic and carcinogenic hydrazine are pretty significant. Herein, a rhodamine dye coupled to naphthalene was selected as a near-infrared fluorophore and acetyl group as a trigger unit for hydrazine sensing with a Stokes shifts of 62 nm. The probe showed about 77-fold NIR fluorescence enhancement in the presence of hydrazine. In addition, the detection limit was as low as 3.4 ppb, and the fluorescence intensity at 654 nm showed a satisfactory linearity with the concentration range of hydrazine from 0 to 120 mu M. More importantly, the practical utility of probe has been successfully proved through the fluorescence bioimaging of hydrazine in living cells with low cytotoxicity and quantitative N-2 H-4 detection in environmental water samples. (C) 2019 Elsevier B.V. All rights reserved.

引用

页数：7