Targeting the assembly of the human immunodeficiency virus type I

被引：27

作者：

Muriaux, D ^{[1
]}

Darlix, JL ^{[1
]}

Cimarelli, A ^{[1
]}

机构：

[1] Ecole Normale Super Lyon, INSERM 412, Unite Virol Humaine, IFR 128,LaboRetro, F-69364 Lyon, France

来源：

CURRENT PHARMACEUTICAL DESIGN | 2004年 / 10卷 / 30期

关键词：

drugs; anti-viral approaches; virion assembly; HIV-1; retrovirus [3;

D O I：

10.2174/1381612043382701

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

In the rush to develop anti-viral drugs against the human immunodeficiency virus type I (HIV-1), all the steps of the viral life cycle are potential targets of therapeutic intervention. In this review, we will explore the recent advances on strategies that aim at obstructing the formation, the release and the infectivity of newly formed virion particles from HIV-1 infected cells.

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收藏

页码：3725 / 3739

页数：15

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