Antimalarial efficacy of nine medicinal plants traditionally used by the Karens of Andaman and Nicobar Islands, India

被引：5

作者：

Chander, M. Punnam ^{[1
]}

Pillai, C. R. ^{[2
]}

Vijayachari, P. ^{[1
]}

机构：

[1] WHO Collaborating Ctr Diag Reference Res & Traini, Indian Council Med Res, Reg Med Res Ctr, Port Blair 744101, Andaman & Nicob, India

[2] Indian Council Med Res, Natl Inst Malaria Res, New Delhi, India

来源：

BANGLADESH JOURNAL OF PHARMACOLOGY | 2016年 / 11卷 / 01期

关键词：

MALARIA; TSUNAMI;

D O I：

10.3329/bjp.v11i1.24055

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The aim of this study was to assess the antimalarial activity of nine medicinal plants used by Karens of Andaman and Nicobar Islands, against Plasmodium falciparum chloroquine-sensitive MRC-2 isolate. The methanol extracts were obtained by cold percolation method and in vitro antimalarial activity was assessed using M-III method. The results indicated that out of nine plant species tested, four plants, viz., Z. spectabilis, S. wallichiana, C. pulcherrima and Amomum sp. demonstrated significant antimalarial activity (50% inhibitory concentration values were 5.5 +/- 0.7, 12.0 +/- 2.5, 14.6 +/- 1.3 and 37.3 +/- 2.5 mu g/mL respectively) with no toxicity effect on erythrocytes.

引用

收藏

页码：126 / 129

页数：4

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