Preparation of sodium cellulose sulfate oligomers by free-radical depolymerization

被引：14

作者：

Muhitdinov, Bahtiyor ^{[1
]}

Heinze, Thomas ^{[2
]}

Normakhamatov, Nodirali ^{[1
]}

Turaev, Abbaskhan ^{[1
]}

机构：

[1] Uzbek Acad Sci, Inst Bioorgan Chem, Lab Polysaccharide Chem, M Ulugbek Str 83, Tashkent 100125, Uzbekistan

[2] Friedrich Schiller Univ Jena, Inst Organ & Macromol Chem, Ctr Excellence Polysaccharide Res, Humboldtstr 10, D-07743 Jena, Germany

来源：

CARBOHYDRATE POLYMERS | 2017年 / 173卷

关键词：

Sodium cellulose sulfate; Sulfation; Free-radical depolymerization; Sulfated oligosaccharide; DOUBLE-STRANDED XANTHAN; ACID-HYDROLYSIS; HYDROGEN-PEROXIDE; POLYSACCHARIDES; DEGRADATION; POLYMERIZATION; HEPARIN;

D O I：

10.1016/j.carbpol.2017.06.033

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Sodium cellulose sulfates with various degree of substitution (DS) and degree of polymerization (DP) were synthesized by homogeneous sulfation of cellulose with different DP by using SO3/pyridine (Py) complex in N,N-dimethylacetamide/lithium chloride (DMA/LiCl). Sodium cellulose sulfate (SCS) samples obtained were free-radically depolymerized with hydrogen peroxide and copper (II) acetate at a controlled pH value of 7.5-8.0 and without control of the pH value (pH 2.5-4.0). The depolymerization process was studied with respect to changes in molecular mass, total DS, and substituent distribution of SCS. Elemental analysis, 13C NMR- and IR spectroscopic methods indicated that primary structures of SCS were retained with insignificant decreases in total sulfate content in the depolymerization. The depolymerization of SCS was randomly and obeyed pseudo first order kinetics under the conditions applied. SCS oligomers with low DP and very narrow molecular weight distribution were prepared by the depolymerization at pH 2.5-4.0. (C) 2017 Elsevier Ltd. All rights reserved.

引用

页码：631 / 637

页数：7

共 44 条

[1] Inhibition of allergic airway responses by heparin derived oligosaccharides: identification of a tetrasaccharide sequence [J].