Synthesis of 3-(2-nitroalkyl) indoles by reaction of 3-(1-arylsulfonylalkyl) indoles with nitroalkanes

被引：21

作者：

Palmieri, Alessandro ^{[1
]}

Petrini, Marino ^{[1
]}

Torregiani, Elisabetta ^{[1
]}

机构：

[1] Univ Camerino, Dipartimento Sci Chim, I-62032 Camerino, Italy

来源：

TETRAHEDRON LETTERS | 2007年 / 48卷 / 32期

关键词：

conjugate addition; imines; indoles; nitroalkanes; sulfones;

D O I：

10.1016/j.tetlet.2007.06.027

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sulfonyl indoles act as effective precursors of vinylogous imino derivatives in the reaction with nitroalkanes under basic conditions leading to the corresponding nitro indoles in good yield. This procedure represents an effective option to the classical conjugate addition of indoles to nitroalkenes. (c) 2007 Elsevier Ltd. All rights reserved.

引用

页码：5653 / 5656

页数：4

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