Identification of two meridianins from the crude extract of the tunicate Aplidium meridianum by tandem mass spectrometryy

被引：59
|
作者：
Seldes, A. M.
Brasco, M. F. Rodriguez
Franco, L. Hernandez
Palermo, J. A.
机构：
[1] Univ Buenos Aires, Fac Ciencias Exactas & Nat, Dept Quim Organ, RA-1428 Buenos Aires, DF, Argentina
[2] Univ Buenos Aires, UMYMFOR, RA-1428 Buenos Aires, DF, Argentina
来源：
NATURAL PRODUCT RESEARCH | 2007年 / 21卷 / 06期
关键词：
meridianins; marine natural products; indole alkaloids; tandem mass spectrometry; constant neutral loss;
D O I：
10.1080/14786410601133517
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
As part of the development of an analytical technique for the detection of meridianins and related compounds in biological fluids, a crude extract of the tunicate Aplidium meridianum was analysed using neutral loss tandem mass spectrometry. The 41 u neutral loss- EI(+) mass spectrum showed molecular ions corresponding to two previously undetected alkaloids. We report herein the isolation and structure elucidation of these alkaloids, meridianins F and G.
引用
收藏
页码：555 / 563
页数：9
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