A unique adolescent response to reward prediction errors

被引:208
作者
Cohen, Jessica R. [3 ]
Asarnow, Robert F. [1 ]
Sabb, Fred W. [1 ,2 ]
Bilder, Robert M. [1 ,2 ,3 ]
Bookheimer, Susan Y. [1 ,2 ,3 ]
Knowlton, Barbara J. [2 ,3 ]
Poldrack, Russell A. [1 ,2 ,3 ]
机构
[1] Univ Calif Los Angeles, Dept Psychiat & Biobehav Sci, Los Angeles, CA 90024 USA
[2] Univ Calif Los Angeles, Brain Res Inst, Los Angeles, CA 90024 USA
[3] Univ Calif Los Angeles, Dept Psychol, Los Angeles, CA USA
关键词
ORBITOFRONTAL CORTEX; DECISION; BRAIN; RISK; ACCUMBENS; STRIATUM; VALUES; ADULTS;
D O I
10.1038/nn.2558
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Previous work has shown that human adolescents may be hypersensitive to rewards, but it is not known which aspect of reward processing is responsible for this. We separated decision value and prediction error signals and found that neural prediction error signals in the striatum peaked in adolescence, whereas neural decision value signals varied depending on how value was modeled. This suggests that heightened dopaminergic prediction error responsivity contributes to adolescent reward seeking.
引用
收藏
页码:669 / 671
页数:3
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