Microwave-assisted efficient synthesis of dihydropyrimidines in solvent-free condition

被引：37
|
作者：
Mirza-Aghayan, M [1 ]
Bolourtchian, M [1 ]
Hosseini, M [1 ]
机构：
[1] CCERCI, Tehran, Iran
来源：
SYNTHETIC COMMUNICATIONS | 2004年 / 34卷 / 18期
关键词：
microwave irradiation; Biginelli compounds; solvent-free condition; ferric chloride hexahydrate;
D O I：
10.1081/SCC-200030577
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of 3,4-dihydropyrimidinones from an aldehyde, a ketoester, and a urea or thiourea using a catalytic amount of ferric chloride hexahydrate is described. Microwave irradiation has been used to accelerate the synthesis of the Biginelli compounds under solvent-free conditions and in a short reaction time and with good yield.
引用
收藏
页码：3335 / 3341
页数：7
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