Microwave-assisted efficient synthesis of dihydropyrimidines in solvent-free condition

被引：37
|
作者：
Mirza-Aghayan, M [1 ]
Bolourtchian, M [1 ]
Hosseini, M [1 ]
机构：
[1] CCERCI, Tehran, Iran
来源：
SYNTHETIC COMMUNICATIONS | 2004年 / 34卷 / 18期
关键词：
microwave irradiation; Biginelli compounds; solvent-free condition; ferric chloride hexahydrate;
D O I：
10.1081/SCC-200030577
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
An efficient synthesis of 3,4-dihydropyrimidinones from an aldehyde, a ketoester, and a urea or thiourea using a catalytic amount of ferric chloride hexahydrate is described. Microwave irradiation has been used to accelerate the synthesis of the Biginelli compounds under solvent-free conditions and in a short reaction time and with good yield.
引用
收藏
页码：3335 / 3341
页数：7
相关论文
共 50 条
  • [1] Microwave-assisted solvent-free heterocyclic synthesis
    Bougrin, K
    Loupy, A
    Soufiaoui, M
    JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY C-PHOTOCHEMISTRY REVIEWS, 2005, 6 (2-3) : 139 - 167
  • [2] Microwave-assisted synthesis of photochromic spirooxazine dyes under solvent-free condition
    Lee, CC
    Wang, JC
    Hu, AT
    MATERIALS LETTERS, 2004, 58 (3-4) : 535 - 538
  • [3] Microwave-assisted conversion of nitriles to thioamides in solvent-free condition
    Moghaddam, FM
    Hojabri, L
    Dohendou, M
    SYNTHETIC COMMUNICATIONS, 2003, 33 (24) : 4279 - 4284
  • [4] Microwave-assisted solvent-free synthesis of (E)-stilbenes
    Wang, Liu-chang
    Li, Jiang
    Zhang, Xi-quan
    Gu, Hong-mei
    Li, Bao-lin
    JOURNAL OF CHEMICAL RESEARCH, 2012, (04) : 231 - 234
  • [5] Microwave-assisted solvent-free synthesis of fluorescent naphthalimide dyes
    Bardajee, Ghasem R.
    DYES AND PIGMENTS, 2013, 99 (01) : 52 - 58
  • [6] Microwave-assisted solvent-free synthesis of some hemicyanine dyes
    Wang, LY
    Zhang, XG
    Shi, YP
    Zhang, ZX
    DYES AND PIGMENTS, 2004, 62 (01) : 21 - 25
  • [7] Microwave-Assisted Catalyst-Free and Solvent-Free Method for the Synthesis of Quinoxalines
    Zhou, Jian-Feng
    Gong, Gui-Xia
    Zhi, San-Jun
    Duan, Xiu-Li
    SYNTHETIC COMMUNICATIONS, 2009, 39 (20) : 3743 - 3754
  • [8] Microwave-assisted, solvent-free synthesis of several quinazoline alkaloid frameworks
    Cledera, Pilar
    Sanchez, Juan Domingo
    Caballero, Esmeralda
    Yates, Tamara
    Ramirez, Elena G.
    Avendano, Carmen
    Ramos, M. Teresa
    Menendez, J. Carlos
    SYNTHESIS-STUTTGART, 2007, (21): : 3390 - 3398
  • [9] Microwave-assisted synthesis of asymmetric thiocarbonohydrazones under solvent-free conditions
    Qing Han Li College of Chemistry and Environmental Protection Engineering
    ChineseChemicalLetters, 2009, 20 (07) : 793 - 796
  • [10] Microwave-assisted synthesis of asymmetric thiocarbonohydrazones under solvent-free conditions
    Li, Qing Han
    CHINESE CHEMICAL LETTERS, 2009, 20 (07) : 793 - 796
12345