Achieving fast timing performance with multiplexed SiPMs

被引:12
作者
Bieniosek, M. F. [1 ,2 ,3 ]
Cates, J. W. [1 ,2 ]
Levin, C. S. [1 ,2 ,3 ,4 ,5 ]
机构
[1] Stanford Univ, Dept Radiol, Stanford, CA 94305 USA
[2] MIPS, Stanford, CA 94305 USA
[3] Stanford Univ, Dept Elect Engn, Stanford, CA 94305 USA
[4] Stanford Univ, Dept Phys, Stanford, CA 94305 USA
[5] Stanford Univ, Dept Bioengn, Stanford, CA 94305 USA
关键词
PET; time-of-flight; multiplexing; SiPM; TIME-OF-FLIGHT; POSITRON-EMISSION-TOMOGRAPHY; SILICON PHOTOMULTIPLIER; PET; DETECTORS;
D O I
10.1088/0031-9155/61/7/2879
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Using time of flight (ToF) measurements for positron emission tomography (PET) is an attractive avenue for increasing the signal to noise (SNR) ratio of PET images. However, achieving excellent time resolution required for high SNR gain using silicon photomultipliers (SiPM) requires many resource heavy high bandwidth readout channels. A method of multiplexing many SiPM signals into a single electronic channel would greatly simplify ToF PET systems. However, multiplexing SiPMs degrades time resolution because of added dark counts and signal shaping. In this work the relative contribution of dark counts and signal shaping to timing degradation is simulated and a baseline correction technique to mitigate the effect of multiplexing on the time resolution of analog SiPMs is simulated and experimentally verified. A charge sharing network for multiplexing is proposed and tested. Results show a full width at half maximum (FWHM) coincidence time resolution of 232 +/- 2 ps for a single 3 mm x 3 mm x 20 mm LYSO scintillation crystals coupled to an array of sixteen 3 mm x 3 mm SiPMs that are multiplexed to a single timing channel (in addition to 4 position channels). A 4x4 array of 3 mm x 3 mm x 20 mm LFS crystals showed an average FWHM coincidence time resolution of 278 +/- 7 ps using the same timing scheme. All experiments were performed at room temperature with no thermal regulation. These results show that excellent time resolution for ToF can be achieved with a highly multiplexed analog SiPM readout.
引用
收藏
页码:2879 / 2892
页数:14
相关论文
共 22 条
  • [1] BUDINGER TF, 1983, J NUCL MED, V24, P73
  • [2] Choe H-J C, 2014, IEEE NUCL SCI S, pM19
  • [3] Dolinsky S, 2010, IEEE NUCL SCI CONF R, P1763, DOI 10.1109/NSSMIC.2010.5874077
  • [4] Investigation of analog charge multiplexing schemes for SiPM based PET block detectors
    Downie, Evan
    Yang, Xin
    Peng, Hao
    [J]. PHYSICS IN MEDICINE AND BIOLOGY, 2013, 58 (11) : 3943 - 3964
  • [5] Study of the response and photon-counting resolution of silicon photomultipliers using a generic simulation framework
    Eckert, P.
    Stamen, R.
    Schultz-Coulon, H. -C.
    [J]. JOURNAL OF INSTRUMENTATION, 2012, 7
  • [6] The Digital Silicon Photomultiplier - Principle of Operation and Intrinsic Detector Performance
    Frach, Thomas
    Prescher, Gordian
    Degenhardt, Carsten
    de Gruyter, Rik
    Schmitz, Anja
    Ballizany, Rob
    [J]. 2009 IEEE NUCLEAR SCIENCE SYMPOSIUM CONFERENCE RECORD, VOLS 1-5, 2009, : 1959 - 1965
  • [7] Analog Circuit for Timing Measurements With Large Area SiPMs Coupled to LYSO Crystals
    Gola, Alberto
    Piemonte, Claudio
    Tarolli, Alessandro
    [J]. IEEE TRANSACTIONS ON NUCLEAR SCIENCE, 2013, 60 (02) : 1296 - 1302
  • [8] 1 SiPM Performance in PET Applications: An Experimental and Theoretical Analysis
    Henseler, Debora
    Grazioso, Ronald
    Zhang, Nan
    Schmand, Matthias
    [J]. 2009 IEEE NUCLEAR SCIENCE SYMPOSIUM CONFERENCE RECORD, VOLS 1-5, 2009, : 1941 - +
  • [9] Benefit of time-of-flight in PET: Experimental and clinical results
    Karp, Joel S.
    Surti, Sulernan
    Daube-Witherspoon, Margaret E.
    Muehllehner, Gerd
    [J]. JOURNAL OF NUCLEAR MEDICINE, 2008, 49 (03) : 462 - 470
  • [10] Kim C, 2012, IEEE NUCL SCI CONF R, P3533