Independent Association of Vitamin D With Physical Function in People With Chronic Spinal Cord Injury

被引：20
作者：
Barbonetti, Arcangelo [1 ,2 ]
Sperandio, Alessandra [1 ]
Micillo, Alessandro [1 ]
D'Andrea, Settimio [1 ]
Pacca, Federica [2 ]
Felzani, Giorgio [2 ]
Francavilla, Sandro [1 ]
Francavilla, Felice [1 ]
机构：
[1] Univ Aquila, Dept Life Hlth & Environm Sci, Androl Unit, Blocco 11, I-67100 Laquila, Italy
[2] San Raffaele Sulmona Inst, Spinal Unit, Sulmona, Italy
来源：
ARCHIVES OF PHYSICAL MEDICINE AND REHABILITATION | 2016年 / 97卷 / 05期
关键词：
Activities of daily living; Paraplegia; Quadriplegia; Rehabilitation; SERUM 25-HYDROXYVITAMIN D; MUSCLE STRENGTH; CLINICAL-PRACTICE; D DEFICIENCY; INPATIENT REHABILITATION; PERFORMANCE; CALCIUM; FALLS; DISABILITY; FRACTURES;
D O I：
10.1016/j.apmr.2016.01.002
中图分类号：
R49 [康复医学];
学科分类号：
100215 ;
摘要：
Objective: To explore the relation between vitamin D and physical function outcomes in people with spinal cord injury (SCI). Design: Cross-sectional study. Setting: Rehabilitation institute. Participants: Consecutive patients (N=100; 72 men and 28 women) with chronic SCI admitted to a rehabilitation program. Interventions: Not applicable. Main Outcome Measures: Functional independence in activities of daily living (ADL) and leisure time physical activity (LTPA) were assessed as measures of physical function. Results: Vitamin D deficiency (<20ng/mL) was found in 78 patients: they exhibited a significantly higher body mass index, lower functional independence in ADL, and were engaged in a significantly poorer weekly LTPA. At the linear multiple regression analysis, lower 25-hydroxyvitamin D levels showed significant independent associations with poorer functional independence in ADL (beta=.59; 95% confidence interval, .36-.82; P<.0001) and with poorer LTPA (beta=2.35; 95% confidence interval, 0.77-3.94; P =.004), after adjustment for other predictors of physical function outcomes selected by univariate analyses. Conclusions: In people with chronic SCI, a low vitamin D level represents an independent predictor of poor physical function. (C) 2016 by the American Congress of Rehabilitation Medicine
引用
收藏
页码：726 / 732
页数：7
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