Antifungal activity of sterols and triterpenes isolated from Ganoderma annulare

被引：68

作者：

Smania, EFA

Delle Monache, F

Smania, A ^{[1
]}

Yunes, RA

Cuneo, RS

机构：

[1] Univ Fed Santa Catarina, Dept Microbiol & Parasitol, BR-88040900 Florianopolis, SC, Brazil

[2] Univ Cattolica Sacro Cuore, Ist Biochim & Biochim Clin, Rome, Italy

[3] Univ Fed Santa Catarina, Dept Quim, BR-88040900 Florianopolis, SC, Brazil

来源：

FITOTERAPIA | 2003年 / 74卷 / 04期

关键词：

Ganoderma annulare; sterols; triterpenes; applanoxidic acids; antifungal activity;

D O I：

10.1016/S0367-326X(03)00064-9

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Three sterols, 5alpha-ergost-7-en-3beta-ol, 5alpha-ergosta-7,22-dien-3beta-ol and 5,8-epidioxy-5alpha,8alpha-ergosta-6,22-dien-3beta-ol and five triterpenes, applanoxidic acids A, C, F, G and H, have been isolated from Ganoderma annulare. The applanoxidic acids A, C and F were found to inhibit the growth of the fungi Microsporum cannis and Trichophyton mentagrophytes at concentrations of 500 to 1000 mug/ml. (C) 2003 Elsevier Science B.V. All rights reserved.

引用

页码：375 / 377

页数：3

共 6 条

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