Myocardial infarction in a neonate Lessons for neonatal and internal medicine

Due to the lack of evidence-based guidelines, management strategies for neonatal Ml should be individualized and administered largely at the discretion of responsible treating teams. Supportive care with a focus on preserving adequate circulation and anti thrombotic therapy with a view to restoring vascular patency are the mainstays of treatment. Thrombolytic therapy of neonatal Ml includes a chance to completely restore myocardial function. Understanding the resilience of the neonatal heart and mechanism of cardiac cell repair in neonates may spark novel treatment strategies for severe Ml in the large number of affected individuals in an aging population.