Cardiovascular epigenome-wide association studies: is epigenetics falling short?

被引：7
作者：
Zaina, Silvio [1 ]
Lund, Gertrud [2 ]
机构：
[1] Univ Guanajuato, Dept Med Sci, Leon 37320, Gto, Mexico
[2] CINVESTAV, Irapuato Unit, Dept Genet Engn, Irapuato, Gto, Mexico
来源：
CURRENT OPINION IN LIPIDOLOGY | 2014年 / 25卷 / 06期
关键词：
LIPID-LOWERING DRUGS; DNA METHYLATION; DIET NETWORK; ATHEROSCLEROSIS; DISEASE; GENE; CELLS;
D O I：
10.1097/MOL.0000000000000133
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：474 / 475
页数：2
相关论文
共 21 条
  • [1] Aslibekyan S, 2014, TRANSL RES
  • [2] DNA methylation and body-mass index: a genome-wide analysis
    Dick, Katherine J.
    Nelson, Christopher P.
    Tsaprouni, Loukia
    Sandling, Johanna K.
    Aissi, Dylan
    Wahl, Simone
    Meduri, Eshwar
    Morange, Pierre-Emmanuel
    Gagnon, France
    Grallert, Harald
    Waldenberger, Melanie
    Peters, Annette
    Erdmann, Jeanette
    Hengstenberg, Christian
    Cambien, Francois
    Goodall, Alison H.
    Ouwehand, Willem H.
    Schunkert, Heribert
    Thompson, John R.
    Spector, Tim D.
    Gieger, Christian
    Tregout, David-Alexandre
    Deloukas, Panos
    Samani, Nilesh J.
    [J]. LANCET, 2014, 383 (9933) : 1990 - 1998
  • [3] Flow-dependent epigenetic DNA methylation regulates endothelial gene expression and atherosclerosis
    Dunn, Jessilyn
    Qiu, Haiwei
    Kim, Soyeon
    Jjingo, Daudi
    Hoffman, Ryan
    Kim, Chan Woo
    Jang, Inhwan
    Son, Dong Ju
    Kim, Daniel
    Pan, Chenyi
    Fan, Yuhong
    Jordan, I. King
    Jo, Hanjoong
    [J]. JOURNAL OF CLINICAL INVESTIGATION, 2014, 124 (07) : 3187 - 3199
  • [4] EPIGENETIC CHANGES MAY CONTRIBUTE TO THE FORMATION AND SPONTANEOUS REGRESSION OF RETINOBLASTOMA
    GREGER, V
    PASSARGE, E
    HOPPING, W
    MESSMER, E
    HORSTHEMKE, B
    [J]. HUMAN GENETICS, 1989, 83 (02) : 155 - 158
  • [5] Epigenome-Wide Association Study of Fasting Measures of Glucose, Insulin, and HOMA-IR in the Genetics of Lipid Lowering Drugs and Diet Network Study
    Hidalgo, Bertha
    Irvin, M. Ryan
    Sha, Jin
    Zhi, Degui
    Aslibekyan, Stella
    Absher, Devin
    Tiwari, Hemant K.
    Kabagambe, Edmond K.
    Ordovas, Jose M.
    Arnett, Donna K.
    [J]. DIABETES, 2014, 63 (02) : 801 - 807
  • [6] Epigenome-Wide Association Study of Fasting Blood Lipids in the Genetics of Lipid-Lowering Drugs and Diet Network Study
    Irvin, Marguerite R.
    Zhi, Degui
    Joehanes, Roby
    Mendelson, Michael
    Aslibekyan, Stella
    Claas, Steven A.
    Thibeault, Krista S.
    Patel, Nikita
    Day, Kenneth
    Jones, Lindsay Waite
    Liang, Liming
    Chen, Brian H.
    Yao, Chen
    Tiwari, Hemant K.
    Ordovas, Jose M.
    Levy, Daniel
    Absher, Devin
    Arnett, Donna K.
    [J]. CIRCULATION, 2014, 130 (07) : 565 - +
  • [7] Local hypomethylation in atherosclerosis found in rabbit ec-sod gene
    Laukkanen, MO
    Mannermaa, S
    Hiltunen, MO
    Aittomäki, S
    Airenne, K
    Jänne, J
    Ylä-Herttuala, S
    [J]. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY, 1999, 19 (09) : 2171 - 2178
  • [8] FOXP3 demethylation as a means of identifying quantitative defects in regulatory T cells in acute coronary syndrome
    Lu, Cai-Xia
    Xu, Ren-De
    Cao, Ming
    Wang, Guan
    Yan, Feng-Qin
    Shang, Sha-Sha
    Wu, Xiao-Fen
    Ruan, Lei
    Quan, Xiao-Qing
    Zhang, Cun-Tai
    [J]. ATHEROSCLEROSIS, 2013, 229 (01) : 263 - 270
  • [9] Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition
    Maunakea, Alika K.
    Chepelev, Iouri
    Cui, Kairong
    Zhao, Keji
    [J]. CELL RESEARCH, 2013, 23 (11) : 1256 - 1269
  • [10] Contribution of genetic variation to transgenerational inheritance of DNA methylation
    McRae, Allan F.
    Powell, Joseph E.
    Henders, Anjali K.
    Bowdler, Lisa
    Hemani, Gibran
    Shah, Sonia
    Painter, Jodie N.
    Martin, Nicholas G.
    Visscher, Peter M.
    Montgomery, Grant W.
    [J]. GENOME BIOLOGY, 2014, 15 (05): : R73
123