Disassembling peptide-based fibres by switching the hydrophobic-hydrophilic balance

被引:20
作者
Meijer, Joris T.
Henckens, Marloes J. A. G.
Minten, Inge J.
Lowik, Dennis W. P. M.
van Hest, Jan C. M.
机构
[1] 6525 ED, Nijmegen
关键词
D O I
10.1039/b708847g
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Amyloid-like model peptides, modified on the N-terminus with an alkyl tail and on the C-terminus with a PEG chain, yielded fibres that were susceptible to triggered disassembly by removal of the alkyl chain, which affected the hydrophobic - hydrophilic balance.
引用
收藏
页码:1135 / 1137
页数:3
相关论文
共 26 条
[1]   Photolabile protecting groups and linkers [J].
Bochet, CG .
JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 2002, (02) :125-142
[2]   Photolytic control of peptide self-assembly [J].
Bosques, CJ ;
Imperiali, B .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2003, 125 (25) :7530-7531
[3]   Formulation of photocleavable liposomes and the mechanism of their content release [J].
Chandra, B ;
Subramaniam, R ;
Mallik, S ;
Srivastava, DK .
ORGANIC & BIOMOLECULAR CHEMISTRY, 2006, 4 (09) :1730-1740
[4]   De novo designed peptide-based amyloid fibrils [J].
de la Paz, ML ;
Goldie, K ;
Zurdo, J ;
Lacroix, E ;
Dobson, CM ;
Hoenger, A ;
Serrano, L .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2002, 99 (25) :16052-16057
[5]   Switch-peptides:: Controlling self-assembly of amyloid β-derived peptides in vitro by consecutive triggering of acyl migrations [J].
Dos Santos, S ;
Chandravarkar, A ;
Mandal, B ;
Mimna, R ;
Murat, K ;
Saucède, L ;
Tella, P ;
Tuchscherer, G ;
Mutter, M .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (34) :11888-11889
[6]   Photodestructible vesicles [J].
Eastoe, J ;
Vesperinas, A ;
Donnewirth, AC ;
Wyatt, P ;
Grillo, I ;
Heenan, RK ;
Davis, S .
LANGMUIR, 2006, 22 (03) :851-853
[7]   Rational design of oligopeptide organizers for the formation of poly(ethylene oxide) nanofibers [J].
Eckhardt, D ;
Groenewolt, M ;
Krause, E ;
Börner, HG .
CHEMICAL COMMUNICATIONS, 2005, (22) :2814-2816
[8]   SOLID-PHASE PEPTIDE-SYNTHESIS UTILIZING 9-FLUORENYLMETHOXYCARBONYL AMINO-ACIDS [J].
FIELDS, GB ;
NOBLE, RL .
INTERNATIONAL JOURNAL OF PEPTIDE AND PROTEIN RESEARCH, 1990, 35 (03) :161-214
[9]   Light-activated hydrogel formation via the triggered folding and self-assembly of a designed peptide [J].
Haines, LA ;
Rajagopal, K ;
Ozbas, B ;
Salick, DA ;
Pochan, DJ ;
Schneider, JP .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2005, 127 (48) :17025-17029
[10]   Solution self-assembly of hybrid block copolymers containing poly(ethylene glycol) and amphiphilic β-strand peptide sequences [J].
Hamley, IW ;
Ansari, A ;
Castelletto, V ;
Nuhn, H ;
Rösler, A ;
Klok, HA .
BIOMACROMOLECULES, 2005, 6 (03) :1310-1315