A new benzopyrans derivative from a mangrove-derived fungus Penicillium citrinum from the South China Sea

被引：27

作者：

Zheng, Cai-Juan ^{[1
]}

Huang, Guo-Lei ^{[1
]}

Xu, Yan ^{[2
]}

Song, Xin-Ming ^{[1
]}

Yao, Jun ^{[1
]}

Liu, Hui ^{[1
]}

Wang, Ruo-Ping ^{[1
]}

Sun, Xue-Ping ^{[2
]}

机构：

[1] Guangxi Inst Oceanol, Guangxi Key Lab Marine Biotechnol, Beihai, Peoples R China

[2] Hainan Normal Univ, Coll Chem & Chem Engn, Key Lab Trop Med Plant Chem, Minist Educ, Haikou, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2016年 / 30卷 / 07期

基金：

中国国家自然科学基金;

关键词：

Penicillium citrinum; metabolites; benzopyran derivative; antibacterial activity; METABOLITES; SP;

D O I：

10.1080/14786419.2015.1072712

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

One new benzopyran derivative (2R(*),4R(*))-3,4-dihydro-5-methoxy-2-methyl-2H-1-benzopyran-4-ol (1), together with five known compounds (2-6), were obtained from the EtOAc extract of the endophytic fungus Penicillium citrinum HL-5126 isolated from the mangrove Brguiera sexangula var. rhynchopetala collected in the South China Sea. Their structures were elucidated by the detailed analysis of comprehensive spectroscopic data. All compounds were evaluated for their antibacterial activities. Compound 6 exhibited potent inhibitory activity against Bacillus subtilis, Bacillus cereus and Micrococcus tetragenus with the same MIC values of 6.94M.

引用

页码：821 / 825

页数：5

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